Evidence map›Paper›PMID 41683901›Full record

ArticleInternational journal of molecular sciences2026

3-Hydroxypropionic Acid Enhances Hair Growth-Related Signaling in Human Follicle Dermal Papilla Cells via Activation of the Wnt/β-Catenin Pathway.

Chae Young Jeon, Yun Hoo Jo, Seung A Woo, Yura Lee, Woochul Jung, Dong Wook Shin

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Chae Young JeonResearch Institute for Biomedical and Health Science, Konkuk University, Chungju 27478, Republic of Korea.
Yun Hoo JoResearch Institute for Biomedical and Health Science, Konkuk University, Chungju 27478, Republic of Korea.
Seung A WooAdvanced Materials R&D Center, LG Chem, 30, Magokjungang 10-ro, Gangseo-gu, Seoul 07796, Republic of Korea.
Yura LeeAdvanced Materials R&D Center, LG Chem, 30, Magokjungang 10-ro, Gangseo-gu, Seoul 07796, Republic of Korea.
Woochul JungAdvanced Materials R&D Center, LG Chem, 30, Magokjungang 10-ro, Gangseo-gu, Seoul 07796, Republic of Korea.
Dong Wook ShinResearch Institute for Biomedical and Health Science, Konkuk University, Chungju 27478, Republic of Korea.ORCID 0000-0002-1262-2566

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hair loss is a common condition that affects a large number of people worldwide, impacting both men and women. Its development is closely linked to the function of hair follicle dermal papilla cells (HFDPCs), which play a pivotal role in maintaining hair growth and follicle integrity. However, these cells are particularly vulnerable to oxidative stress generated under psychological or environmental stressful conditions. Preserving the mitochondrial function and biological activity of HFDPCs is critical for preventing stress-related hair loss. This study investigated the protective and hair growth-promoting effects of 3-hydroxypropionic acid (3-HP), a naturally occurring organic acid with antioxidant potential, on HFDPCs exposed to H

Indexed as

DermisHairHair FollicleLactic AcidWnt Signaling Pathwaybeta CateninCell MovementCells, CulturedCell SurvivalHumansHydrogen PeroxideMembrane Potential, MitochondrialOxidative StressReactive Oxygen Speciesbeta CateninHydrogen PeroxideLactic AcidReactive Oxygen Species3-hydroxypropionic acidhair growthhuman follicle dermal papilla cellsoxidative stressWnt/β-catenin signaling

Identifiers

PMID41683901
PMCPMC12898851

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.