Evidence map›Paper›PMID 41683821›Full record

ArticleInternational journal of molecular sciences2026

Isolation and Characterization of 5-(1-Hydroxyethyl)-Dihydro-2-Furanone from

Lapamas Rueankham, Natsima Viriyaadhammaa, Wenxian Yin, Yuanzhi Liu, Sawitree Chiampanichayakul, Methee Rungrojsakul, Trinnakorn Katekunlaphan, Siriporn Okonogi, Aroonchai Saiai, Arihiro Iwasaki and 3 more

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Lapamas RueankhamDepartment of Medical Technology, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai 50200, Thailand.
Natsima ViriyaadhammaaDepartment of Medical Technology, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai 50200, Thailand.ORCID 0009-0004-7955-3712
Wenxian YinDepartment of Medical Technology, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai 50200, Thailand.ORCID 0000-0003-2586-4545
Yuanzhi LiuDepartment of Pharmacy, The Affiliated Hospital, Southwest Medical University, Luzhou 646000, China.
Sawitree ChiampanichayakulDepartment of Medical Technology, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai 50200, Thailand.ORCID 0000-0002-3452-8511
Methee RungrojsakulDepartment of Traditional Chinese Medicine, Faculty of Science, Chandrakasem Rajabhat University, Bangkok 10900, Thailand.
Trinnakorn KatekunlaphanDepartment of Chemistry, Faculty of Science, Chandrakasem Rajabhat University, Bangkok 10900, Thailand.
Siriporn OkonogiCenter of Excellence in Pharmaceutical Nanotechnology, Faculty of Pharmacy, Chiang Mai University, Chiang Mai 50200, Thailand.ORCID 0000-0001-6077-5017
Aroonchai SaiaiDepartment of Chemistry, Faculty of Science, Chiang Mai University, Chiang Mai 50200, Thailand.ORCID 0000-0002-0155-9952
Arihiro IwasakiDepartment of Applied Chemistry, Faculty of Science and Engineering, Chuo University, Tokyo 112-8551, Japan.ORCID 0000-0002-3775-5066
Christian Nanga ChickDepartment of Materials and Life Sciences, Faculty of Science and Technology, Sophia University, Tokyo 102-8554, Japan.ORCID 0009-0004-6716-7718
Toyonobu UsukiDepartment of Materials and Life Sciences, Faculty of Science and Technology, Sophia University, Tokyo 102-8554, Japan.ORCID 0000-0002-0212-5371
Songyot AnuchapreedaDepartment of Medical Technology, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai 50200, Thailand.ORCID 0000-0001-7259-4694

Funding

Fundamental Fund 69 214477/R68IN00697National Research Council of Thailand (NRCT) through the Royal Golden Jubilee Ph.D. Program of Thailand NRCT5-RGJ63004
6 · The paper itself

Abstract

Acute myeloid leukemia (AML) is a heterogeneous hematological malignancy with poor prognosis, frequent relapse, and treatment-related toxicity. The discovery of novel anti-leukemic agents with improved selectivity remains an urgent clinical need. In this study, rhizomes of

Indexed as

Anti-Inflammatory AgentsAntineoplastic Agents, PhytogenicFuransLeukemia, Myeloid, AcutePlant ExtractsAnimalsApoptosisCell Cycle CheckpointsCell Line, TumorCell ProliferationHumansMiceMolecular Docking SimulationAnti-Inflammatory AgentsAntineoplastic Agents, PhytogenicFuransPlant Extractsacute myeloid leukemiaAngiopteris evectaanti-inflammatory activityapoptosiscell cycle arrestfuranone derivativesMAPK signalingmolecular dockingnetwork pharmacologyternary mixtureWT1

Identifiers

PMID41683821
PMCPMC12897760

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.