Evidence map›Paper›PMID 41683734›Full record

ArticleInternational journal of molecular sciences2026

The Local Damage and Systemic Inflammation Induced by a Biodegradable Polydioxanone Stent Implanted in the Rabbit Trachea Decreases Markedly with Stent Degradation.

Carolina Serrano-Casorran, Sergio Rodriguez-Zapater, Francisco Rodriguez-Panadero, Raquel Gomez, Cristina Bonastre, Jose Andres Guirola, Jose Rodriguez, Miguel Angel de Gregorio

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Carolina Serrano-CasorranMinimally Invasive Research Group (GITMI), Universidad de Zaragoza, 50009 Zaragoza, Spain.ORCID 0000-0002-8880-6580
Sergio Rodriguez-ZapaterMinimally Invasive Research Group (GITMI), Universidad de Zaragoza, 50009 Zaragoza, Spain.ORCID 0000-0003-3880-3821
Francisco Rodriguez-PanaderoInstituto de Biomedicina de Sevilla (IbiS), Hospital Universitario Virgen del Rocío, CSIC-Universidad de Sevilla, 41013 Sevilla, Spain.ORCID 0000-0002-9640-7926
Raquel GomezInstituto de Biomedicina de Sevilla (IbiS), Hospital Universitario Virgen del Rocío, CSIC-Universidad de Sevilla, 41013 Sevilla, Spain.ORCID 0009-0002-4026-1304
Cristina BonastreMinimally Invasive Research Group (GITMI), Universidad de Zaragoza, 50009 Zaragoza, Spain.ORCID 0000-0001-6178-9891
Jose Andres GuirolaMinimally Invasive Research Group (GITMI), Universidad de Zaragoza, 50009 Zaragoza, Spain.ORCID 0000-0002-0113-5121
Jose RodriguezMinimally Invasive Research Group (GITMI), Universidad de Zaragoza, 50009 Zaragoza, Spain.ORCID 0000-0001-9605-4959
Miguel Angel de GregorioMinimally Invasive Research Group (GITMI), Universidad de Zaragoza, 50009 Zaragoza, Spain.ORCID 0000-0002-5618-7519

Funding

Government of Aragón Ref. Group B36_23R
6 · The paper itself

Abstract

Biodegradable tracheal stents have been developed to overcome the limitations of metallic and removable stents in benign airway disease. This study evaluated the local and systemic inflammatory response induced by a biodegradable polydioxanone tracheal stent in a rabbit model. Twenty-one rabbits were assigned to three follow-up groups (30, 60, and 90 days). In each group, six animals received a tracheal stent, and one served as a sham control. Clinical status and respiratory symptoms were monitored, and serial peripheral blood interleukin-8 (IL-8) levels were measured. At the end of follow-up, tracheoscopy, IL-8 quantification in tracheal lavage, and necropsy were performed. No deaths or severe respiratory symptoms occurred. Tracheoscopic findings were significantly less severe after stent degradation, with reduced congestion (

Indexed as

Absorbable ImplantsInflammationPolydioxanoneStentsTracheaAnimalsInterleukin-8MaleRabbitsInterleukin-8Polydioxanoneabsorbable implantsanimalcytokinesinterleukin-8modelspolydioxanonestentstracheal stenosis

Identifiers

PMID41683734
PMCPMC12898746

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.