ArticleInternational journal of molecular sciences2026
Lymphoid Organ Architecture and Hematopoiesis Disruption in Spinal Muscular Atrophy: Therapeutic Rescue by SMN Restoration.
Paula Guillamón, Georg Lindner, Joel Guillen, Alaó Gatius, Sílvia Gras, Laura Martínez-España, Lídia Piedrafita, Anaïs Panosa, Olga Tapia, Conchi Mora and 4 more
Abstract read
In one paragraphArticle in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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What it found
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2 · The registryThe trial behind it
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3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
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4 · The recordCorrections and comments
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5 · Who and what moneyAuthors and funding
14 authors.
Paula GuillamónExperimental Neuromuscular Pathology Unit, Departament de Medicina Experimental, Facultat de Medicina, Universitat de Lleida, Av. Rovira Roure 80, 25198 Lleida, CAT, Spain.ORCID 0009-0009-9494-1584 Georg LindnerMedicine Genetics Group, Vall d'Hebron Research Institute (VHIR), Esfera UAB, 08035 Barcelona, CAT, Spain.ORCID 0009-0005-7766-4846 Joel GuillenExperimental Neuromuscular Pathology Unit, Departament de Medicina Experimental, Facultat de Medicina, Universitat de Lleida, Av. Rovira Roure 80, 25198 Lleida, CAT, Spain.ORCID 0009-0005-2450-7732 Alaó GatiusExperimental Neuromuscular Pathology Unit, Departament de Medicina Experimental, Facultat de Medicina, Universitat de Lleida, Av. Rovira Roure 80, 25198 Lleida, CAT, Spain.ORCID 0000-0002-5153-1181 Sílvia GrasExperimental Neuromuscular Pathology Unit, Departament de Medicina Experimental, Facultat de Medicina, Universitat de Lleida, Av. Rovira Roure 80, 25198 Lleida, CAT, Spain.
Laura Martínez-EspañaExperimental Neuromuscular Pathology Unit, Departament de Medicina Experimental, Facultat de Medicina, Universitat de Lleida, Av. Rovira Roure 80, 25198 Lleida, CAT, Spain.
Lídia PiedrafitaExperimental Neuromuscular Pathology Unit, Departament de Medicina Experimental, Facultat de Medicina, Universitat de Lleida, Av. Rovira Roure 80, 25198 Lleida, CAT, Spain.
Anaïs PanosaInstitut de Recerca Biomèdica de Lleida-Fundació Dr. Pifarré, IRBLleida, 25198 Lleida, CAT, Spain.
Olga TapiaDepartment of Basic Medical Sciences, Institute of Biomedical Technologies (ITB), Universidad de La Laguna (ULL), 38200 Tenerife, CAN, Spain.ORCID 0000-0002-0802-7975 Conchi MoraInstitut de Recerca Biomèdica de Lleida-Fundació Dr. Pifarré, IRBLleida, 25198 Lleida, CAT, Spain.
Josep E EsquerdaInstitut de Recerca Biomèdica de Lleida-Fundació Dr. Pifarré, IRBLleida, 25198 Lleida, CAT, Spain.
Eduardo F TizzanoMedicine Genetics Group, Vall d'Hebron Research Institute (VHIR), Esfera UAB, 08035 Barcelona, CAT, Spain.
Olga TarabalExperimental Neuromuscular Pathology Unit, Departament de Medicina Experimental, Facultat de Medicina, Universitat de Lleida, Av. Rovira Roure 80, 25198 Lleida, CAT, Spain.ORCID 0000-0001-7741-3223 Jordi CalderóExperimental Neuromuscular Pathology Unit, Departament de Medicina Experimental, Facultat de Medicina, Universitat de Lleida, Av. Rovira Roure 80, 25198 Lleida, CAT, Spain.ORCID 0000-0003-1972-0115 Funding
FI-SDUR-2023 fellowship 00036FPI-MCIN fellowship PRE2022-102424Fundació La Marató de 3Cat 202005-30Ministerio de Ciencia e Innovación (MCIN) / FEDER PID2021-122785OBI00Ministerio de Ciencia e Innovación (MCIN) / FEDER PID2021-126820OB-I00
6 · The paper itselfAbstract
Spinal muscular atrophy (SMA) is a neuromuscular disorder caused by loss of the
Indexed as
HematopoiesisLymphoid TissueMuscular Atrophy, SpinalSurvival of Motor Neuron 1 ProteinSurvival of Motor Neuron 2 ProteinAnimalsBone MarrowDisease Models, AnimalHumansMiceOligonucleotides, AntisenseSpleenThymus GlandOligonucleotides, AntisenseSmn1 protein, mouseSMN2 protein, mouseSurvival of Motor Neuron 1 ProteinSurvival of Motor Neuron 2 Proteinbone marrowhumanimmune systemSMASMN∆7 mouseSMN-ASO therapyspleenthymus
Identifiers
PMID41683702
PMCPMC12897893
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