ArticleInternational journal of molecular sciences2026
Runx2 in the Perichondrial Osteoblasts Enhances Terminal Differentiation of Chondrocytes Through
Xin Qin, Qing Jiang, Longfei Wu, Suemi Yabuta, Chiharu Sakane, Yuki Matsuo, Ziheng Zhang, Hisato Komori, Manyu Zhang, Kosei Ito and 1 more
Abstract read
In one paragraphArticle in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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5 · Who and what moneyAuthors and funding
11 authors.
Qing JiangInstitute of Orthopaedics, Suzhou Medical College, Soochow University, Suzhou 215006, China.ORCID 0000-0003-1875-6263 Longfei WuCenter for Genetic Epidemiology and Genomics, School of Public Health, Suzhou Medical College, Soochow University, Suzhou 215006, China.
Suemi YabutaDepartment of Molecular Tumor Biology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki 852-8588, Japan.
Chiharu SakaneResearch Center for Biomedical Models and Animal Welfare, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki 852-8588, Japan.ORCID 0000-0002-6895-0577 Yuki MatsuoDepartment of Molecular Tumor Biology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki 852-8588, Japan.
Ziheng ZhangInstitute of Orthopaedics, Suzhou Medical College, Soochow University, Suzhou 215006, China.
Hisato KomoriDepartment of Molecular Tumor Biology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki 852-8588, Japan.
Manyu ZhangInstitute of Orthopaedics, Suzhou Medical College, Soochow University, Suzhou 215006, China.
Kosei ItoDepartment of Molecular Tumor Biology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki 852-8588, Japan.ORCID 0000-0002-8416-2466 Toshihisa KomoriDepartment of Molecular Tumor Biology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki 852-8588, Japan.
Funding
Japanese Ministry of Education, Culture, Sports, Science and Technology 24K19001), C.S. (22K11805), Y.M. (24K12356), H.K. (23K08591), and T.K. (23H00440)Natural Science Foundation of Jiangsu Province Q. J. (SL24700224)Suzhou Science and Technology Program Project X.Q. (SYW2025086)
6 · The paper itselfAbstract
Runx2 plays essential roles in osteoblast differentiation and chondrocyte maturation. Runx2 in the perichondrium has been reported to inhibit chondrocyte maturation through
Indexed as
Calcium-Binding ProteinsCell DifferentiationChondrocytesCore Binding Factor Alpha 1 SubunitNerve Tissue ProteinsOsteoblastsAnimalsChondrogenesisMiceCalcium-Binding ProteinsCore Binding Factor Alpha 1 SubunitNell1 protein, mouseNerve Tissue ProteinsRunx2 protein, mousechondrocyte differentiationendochondral ossificationNell1perichondriumRunx2terminal hypertrophic chondrocytes
Identifiers
PMID41683693
PMCPMC12898123
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