Evidence map›Paper›PMID 41683664›Full record

ArticleInternational journal of molecular sciences2026

Acute Kidney Injury Post-Liver Transplant Using Grafts Treated with Hypothermic Machine Perfusion: From Biology to Surgical Aspects.

Irene Scalera, Grazia Labellarte, Oronzo Ligurgo, Francesco D'Amico, Gianluigi Gigante, Stefania Roselli, Maria Filippa Valentini, Rossana Franzin, Alessandra Stasi, Loreto Gesualdo and 1 more

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Irene ScaleraHepatobiliary and Liver Transplant Unit, University Hospital Policlinic of Bari, 70124 Bari, Italy.ORCID 0000-0002-4244-9311
Grazia LabellarteHepatobiliary and Liver Transplant Unit, University Hospital Policlinic of Bari, 70124 Bari, Italy.ORCID 0000-0003-2898-8164
Oronzo LigurgoHepatobiliary and Liver Transplant Unit, University Hospital Policlinic of Bari, 70124 Bari, Italy.ORCID 0009-0002-2898-6927
Francesco D'AmicoHepatobiliary and Liver Transplant Unit, University Hospital Policlinic of Bari, 70124 Bari, Italy.ORCID 0000-0001-6915-9755
Gianluigi GiganteHepatobiliary and Liver Transplant Unit, University Hospital Policlinic of Bari, 70124 Bari, Italy.
Stefania RoselliHepatobiliary and Liver Transplant Unit, University Hospital Policlinic of Bari, 70124 Bari, Italy.
Maria Filippa ValentiniHepatobiliary and Liver Transplant Unit, University Hospital Policlinic of Bari, 70124 Bari, Italy.
Rossana FranzinNephrology, Dialysis and Transplant Department, University Hospital Policlinic of Bari, 70124 Bari, Italy.
Alessandra StasiNephrology, Dialysis and Transplant Department, University Hospital Policlinic of Bari, 70124 Bari, Italy.
Loreto GesualdoDepartment of Precision and Regenerative Medicine and Ionian Area, University of Bari, 70121 Bari, Italy.
Francesco TandoiHepatobiliary and Liver Transplant Unit, University Hospital Policlinic of Bari, 70124 Bari, Italy.ORCID 0000-0003-3166-6684

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Many advantages have been reported with the use of machine perfusion (MP) to rescue extended criteria donor (ECD) grafts, improving both short- and long-term post-liver transplantation (LT) outcomes. Acute kidney injury (AKI) is a common post-LT complication associated with these grafts and may compromise patient outcomes and increase LT-related costs. The aim of the study was to analyze the incidence of AKI in recipients of MP-treated grafts compared with those receiving conventionally cold-stored (SCS) grafts, both before and after a propensity score matching (PSM). From a prospectively maintained database, LT recipients of MP-treated grafts were compared with SCS grafts transplanted in the same study period (January 2022-May 2025). PSM was performed based on donor risk index (DRI), macrosteatosis (≥ or <30%), and recipient NaMELD score using a 3:1 (MP vs. SCS) ratio. Of the 177 consecutive LTs, 30 were performed with MP-treated grafts (MP group) and 147 using SCS (SCS group). The MP group displayed more marginal characteristics: older age (72 vs. 62 years,

Indexed as

Acute Kidney InjuryLiver TransplantationOrgan PreservationPerfusionAgedFemaleHumansMaleMiddle Agedacute kidney injuryischemia–reperfusion injuryliver transplantationmachine perfusion

Identifiers

PMID41683664
PMCPMC12897803

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.