Evidence map›Paper›PMID 41683660›Full record

ArticleInternational journal of molecular sciences2026

Functional and Epigenomic Consequences of

Jun-Hui Yuan, Yujiro Higuchi, Masahiro Ando, Akiko Yoshimura, Satoshi Nozuma, Yusuke Sakiyama, Takashi Kanda, Masahiro Nomoto, Takeshi Nakamura, Yasuyuki Nobuhara and 1 more

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Jun-Hui YuanDepartment of Neurology and Geriatrics, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima 890-8520, Japan.ORCID 0000-0002-3808-7813
Yujiro HiguchiDepartment of Neurology and Geriatrics, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima 890-8520, Japan.
Masahiro AndoDepartment of Neurology and Geriatrics, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima 890-8520, Japan.ORCID 0000-0002-6187-9042
Akiko YoshimuraDepartment of Neurology and Geriatrics, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima 890-8520, Japan.
Satoshi NozumaDepartment of Neurology and Geriatrics, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima 890-8520, Japan.ORCID 0000-0002-4909-7769
Yusuke SakiyamaDepartment of Neurology and Geriatrics, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima 890-8520, Japan.
Takashi KandaDepartment of Neurology and Clinical Neuroscience, Yamaguchi University Graduate School of Medicine, Yamaguchi 755-8505, Japan.
Masahiro NomotoDepartment of Neurology and Clinical Pharmacology, Ehime University Graduate School of Medicine, Toon 791-0295, Japan.
Takeshi NakamuraDepartment of Neurology, Osaka Red Cross Hospital, Osaka 543-8555, Japan.
Yasuyuki NobuharaDepartment of Neurology, National Hospital Organization Minami-kyushu Hospital, Kagoshima 899-5293, Japan.
Hiroshi TakashimaDepartment of Neurology and Geriatrics, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima 890-8520, Japan.ORCID 0000-0003-0989-6141

Funding

Japan Agency for Medical Research and Development 201442014A, 201442071AJapan Society for the Promotion of Science JP18H02742, JP20K16604, JP21K15702, JP21H02842, JP22K15713, JP22K07495, JP22K07519Ministry of Health, Labour and Welfare, Japan 20317603, 201610002B
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

DNA (Cytosine-5-)-Methyltransferase 1Epigenesis, GeneticNervous System Diseases5-MethylcytosineCpG IslandsDNA MethylationEpigenomicsFemaleHEK293 CellsHumansMale5-MethylcytosineDNA (Cytosine-5-)-Methyltransferase 1DNMT1 protein, human5mCDNMT1methylationsensory neuropathyspinocerebellar ataxia

Identifiers

PMID41683660
PMCPMC12898541

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.