Evidence map›Paper›PMID 41683600›Full record

ArticleInternational journal of molecular sciences2026

Dialdehyde Alginate as a Crosslinker for Chitosan/Starch Films: Toward Biocompatible and Antioxidant Wound Dressing Materials.

Sylwia Grabska-Zielińska, Marek Pietrzak, Lidia Zasada, Krzysztof Łukowicz, Agnieszka Basta-Kaim, Marta Michalska-Sionkowska, Marcin Wekwejt, Beata Kaczmarek-Szczepańska

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Sylwia Grabska-ZielińskaFaculty of Chemical Technology and Engineering, Bydgoszcz University of Science and Technology, Seminaryjna 3, 85-326 Bydgoszcz, Poland.ORCID 0000-0003-3957-9542
Marek PietrzakFaculty of Chemical Technology and Engineering, Bydgoszcz University of Science and Technology, Seminaryjna 3, 85-326 Bydgoszcz, Poland.ORCID 0000-0001-6985-9858
Lidia ZasadaLaboratory for Functional Polymeric Materials, Faculty of Chemistry, Nicolaus Copernicus University in Toruń, Gagarin 7, 87-100 Toruń, Poland.ORCID 0000-0001-8340-987X
Krzysztof ŁukowiczLaboratory of Immunoendocrinology, Department of Experimental Neuroendocrinology, Maj Institute of Pharmacology, Polish Academy of Sciences, 12 Smętna St., 31-343 Kraków, Poland.ORCID 0000-0003-3186-121X
Agnieszka Basta-KaimLaboratory of Immunoendocrinology, Department of Experimental Neuroendocrinology, Maj Institute of Pharmacology, Polish Academy of Sciences, 12 Smętna St., 31-343 Kraków, Poland.ORCID 0000-0002-3109-0040
Marta Michalska-SionkowskaDepartment of Environmental Microbiology and Biotechnology, Faculty of Biological and Veterinary Sciences, Nicolaus Copernicus University in Toruń, Lwowska 1, 87-100 Toruń, Poland.ORCID 0000-0002-5851-734X
Marcin WekwejtDepartment of Biomaterials Technology, Faculty of Mechanical Engineering and Ship Technology, Gdańsk University of Technology, 80-222 Gdańsk, Poland.ORCID 0000-0002-6889-7825
Beata Kaczmarek-SzczepańskaLaboratory for Functional Polymeric Materials, Faculty of Chemistry, Nicolaus Copernicus University in Toruń, Gagarin 7, 87-100 Toruń, Poland.ORCID 0000-0002-2563-2376

Funding

National Science Centre 2023/07/X/NZ3/01019
6 · The paper itself

Abstract

Biopolymer-based films have attracted increasing attention as sustainable and bioactive materials for wound management. Among them, chitosan (CTS) and starch (ST) blend represent promising candidate due to their natural origin, biodegradability, and intrinsic biological activity; however, their mechanical weakness and limited stability necessitate additional modification. This study reports the development and characterization of CTS-ST thin films crosslinked with dialdehyde alginate (ADA), synthesized via controlled oxidation. Two ADA variants differing in aldehyde group content were prepared to investigate the effect of crosslinking on the structural, physicochemical, and biological performance of the materials. The films were fabricated by blending 2%

Indexed as

AlginatesAntioxidantsBandagesBiocompatible MaterialsChitosanCross-Linking ReagentsStarchHemolysisHumansKeratinocytesSpectroscopy, Fourier Transform InfraredWound HealingAlginatesAntioxidantsBiocompatible MaterialsChitosanCross-Linking ReagentsStarchchitosandialdehyde alginatestarchwound dressing

Identifiers

PMID41683600
PMCPMC12897587

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.