Evidence map›Paper›PMID 41683491›Full record

ReviewMolecules (Basel, Switzerland)2026

DNA Nanostructure-Assembled Metallic Nanoparticles for Biosensing Applications.

Shaokang Ren, Kai He, Canlin Cui, Haoyu Fan, Hongzhen Peng, Kai Jiao, Lihua Wang

Abstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Shaokang RenInstitute of Materiobiology, College of Sciences, Shanghai University, Shanghai 200444, China.
Kai HeInstitute of Materiobiology, College of Sciences, Shanghai University, Shanghai 200444, China.
Canlin CuiInstitute of Materiobiology, College of Sciences, Shanghai University, Shanghai 200444, China.
Haoyu FanInstitute of Materiobiology, College of Sciences, Shanghai University, Shanghai 200444, China.ORCID 0009-0005-0059-5299
Hongzhen PengInstitute of Materiobiology, College of Sciences, Shanghai University, Shanghai 200444, China.
Kai JiaoInstitute of Materiobiology, College of Sciences, Shanghai University, Shanghai 200444, China.
Lihua WangInstitute of Materiobiology, College of Sciences, Shanghai University, Shanghai 200444, China.

Funding

National Key R&D Program of China 2023YFB3208200National Natural Science Foundation of China 22393931
6 · The paper itself

Abstract

DNA nanotechnology offers an unprecedented level of structural programmability for organizing metallic nanoparticles into precisely defined architectures, providing a powerful platform for plasmonic biosensing. In particular, gold and silver nanoparticles assembled on DNA nanostructures enable nanometer-scale control over interparticle distance, orientation, and spatial symmetry, which directly govern collective plasmonic behaviors and optical signal transduction. This review summarizes recent advances in DNA nanostructure-mediated assembly of metal nanoparticles, with an emphasis on design principles and assembly strategies that enable static and dynamic control of nanoparticle organization. Representative examples are discussed to illustrate how well-defined plasmonic assemblies give rise to tunable optical responses, including localized surface plasmon resonance modulation, chiroptical signals, fluorescence enhancement or quenching, and surface-enhanced Raman scattering. The role of structural programmability and stimulus-responsive reconfiguration in translating molecular recognition events into amplified optical outputs is highlighted in the context of biosensing. Finally, current challenges and future perspectives are outlined, focusing on structural robustness, signal reproducibility, and integration toward practical and multiplexed biosensing platforms.

Indexed as

Biosensing TechniquesDNADNA NanostructuresMetal NanoparticlesGoldSilverSpectrum Analysis, RamanSurface Plasmon ResonanceDNAGoldSilverbiosensingDNA nanostructuresmetal nanoparticlesplasmonic properties

Identifiers

PMID41683491
PMCPMC12899497

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.