Evidence map›Paper›PMID 41683464›Full record

ArticleMolecules (Basel, Switzerland)2026

Synthesis and Radioprotective Activity of Benzyl Sulfoxide/Sulfone Coumarins Derived from Ex-RAD.

Tao Wang, Chunrui Zhou, Ningfan Liu, Tao Peng, Lin Wang, Shouguo Zhang

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Tao WangSchool of Chemistry and Chemical Engineering, Henan Institute of Science and Technology, Xinxiang 453003, China.
Chunrui ZhouSchool of Chemistry and Chemical Engineering, Henan Institute of Science and Technology, Xinxiang 453003, China.
Ningfan LiuSchool of Chemistry and Chemical Engineering, Henan Institute of Science and Technology, Xinxiang 453003, China.
Tao PengBeijing Institute of Radiation Medicine, Beijing 100850, China.
Lin WangBeijing Institute of Radiation Medicine, Beijing 100850, China.
Shouguo ZhangBeijing Institute of Radiation Medicine, Beijing 100850, China.

Funding

Beijing Natural Science Foundation of China 7242207Henan Postdoctoral Foundation HN2025102Henan Scientific and Technological Research Projects 252102111109National Natural Science Foundation of China 81273431
6 · The paper itself

Abstract

In order to identify promising radioprotector candidates, a series of benzyl sulfoxide/sulfone coumarin derivatives were designed and synthesized based on the reported activity of Ex-Rad. Most of the target compounds demonstrated significant radioprotective effects at concentrations of 40 μmol/L and 20 μmol/L in HUVECs. Among them, compounds

Indexed as

CoumarinsRadiation-Protective AgentsSulfonesSulfoxidesAnimalsCell SurvivalDNA DamageHumansHuman Umbilical Vein Endothelial CellsMiceMolecular StructureCoumarinsRadiation-Protective AgentsSulfonesSulfoxidesalkaline comet assaycoumarin derivativesmice survivalradioprotection

Identifiers

PMID41683464
PMCPMC12899614

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.