Evidence map›Paper›PMID 41683461›Full record

ReviewMolecules (Basel, Switzerland)2026

Methodologies for Assessing Chemical Toxicity to Aquatic Microorganisms: A Comparative Review.

Hong Chen, Yao Li, Quanzhan Chen, Changyun Chen, Yaojuan Hu

Abstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Hong ChenJiangsu Key Laboratory of Zero-Carbon Energy Development and System Integration, School of Environmental Science, Nanjing Xiaozhuang University, Nanjing 211171, China.
Yao LiJiangsu Key Laboratory of Zero-Carbon Energy Development and System Integration, School of Environmental Science, Nanjing Xiaozhuang University, Nanjing 211171, China.
Quanzhan ChenJiangsu Key Laboratory of Zero-Carbon Energy Development and System Integration, School of Environmental Science, Nanjing Xiaozhuang University, Nanjing 211171, China.
Changyun ChenJiangsu Key Laboratory of Zero-Carbon Energy Development and System Integration, School of Environmental Science, Nanjing Xiaozhuang University, Nanjing 211171, China.
Yaojuan HuJiangsu Key Laboratory of Zero-Carbon Energy Development and System Integration, School of Environmental Science, Nanjing Xiaozhuang University, Nanjing 211171, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aquatic ecological issues have garnered significant attention in recent years, driving the demand for convenient, effective, and systematic assessment methods in environmental risk evaluation. This review provides a comprehensive introduction to methodologies for assessing the toxicity of chemicals toward aquatic microorganisms, which include viruses, bacteria, fungi, protozoa, and algae. Among these, microalgae are commonly used as model organisms due to their relative simplicity. The article details conventional biological methods, general chemical techniques, modern instrumental analyses, and informatics approaches, with a particular focus on algae and bacteria as model organisms for toxicity assessment. The principles, advantages, and limitations of each method are discussed, along with examples of their application in various contexts. Biological methods offer direct visualization, convenience, and rapid results, while modern instrumental techniques enable mechanistic insights at molecular and biochemical levels. Informatics methods facilitate toxicity evaluation in complex systems. While aquatic microorganisms encompass viruses, fungi, protozoa, bacteria, and algae, this review primarily focuses on bacteria and algae as model organisms due to their ecological relevance, sensitivity, and widespread use in standardized assays.

Indexed as

Aquatic OrganismsToxicity TestsWater Pollutants, ChemicalBacteriaFungiMicroalgaeVirusesWater Pollutants, Chemicalaquatic microorganismsmass spectrometrynanobiochipsspectroscopiestoxicity assessment

Identifiers

PMID41683461
PMCPMC12899047

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.