ArticleMolecules (Basel, Switzerland)2026
Synthesis, Antimicrobial Activity and Cytotoxicity of Novel (Piperidin-4-yl)adamantane-1-carboxylate
Kaldybay D Praliyev, Gulmira S Akhmetova, Ulzhalgas B Issayeva, Samir A Ross, Manas T Omyrzakov, Ilya S Korotetskiy, Ardak B Jumagaziyeva, Aigul E Malmakova, Tulegen M Seilkhanov, Ubaidilla M Datkhayev and 4 more
Abstract read
In one paragraphArticle in Molecules (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
14 authors.
Kaldybay D PraliyevLaboratory of Synthetic and Natural Medicinal Compounds Chemistry, A.B. Bekturov Institute of Chemical Sciences JSC, 106 Sh. Ualikhanov St., Almaty 050010, Kazakhstan.ORCID 0000-0003-0381-7481 Gulmira S AkhmetovaLaboratory of Synthetic and Natural Medicinal Compounds Chemistry, A.B. Bekturov Institute of Chemical Sciences JSC, 106 Sh. Ualikhanov St., Almaty 050010, Kazakhstan.ORCID 0000-0002-9074-1464 Ulzhalgas B IssayevaLaboratory of Synthetic and Natural Medicinal Compounds Chemistry, A.B. Bekturov Institute of Chemical Sciences JSC, 106 Sh. Ualikhanov St., Almaty 050010, Kazakhstan.ORCID 0000-0001-6976-6096 Samir A RossNational Center for Natural Products Research, School of Pharmacy, The University of Mississippi, Oxford, MS 38677, USA.ORCID 0000-0002-3807-1299 Manas T OmyrzakovSchool of Pharmacy, Asfendiyarov Kazakh National Medical University, Almaty 050000, Kazakhstan.ORCID 0000-0002-2665-178X Aigul E MalmakovaLaboratory of Synthetic and Natural Medicinal Compounds Chemistry, A.B. Bekturov Institute of Chemical Sciences JSC, 106 Sh. Ualikhanov St., Almaty 050010, Kazakhstan.ORCID 0000-0001-9996-9476 Tulegen M SeilkhanovThe Laboratory of Engineering Profile of NMR Spectroscopy, Sh. Ualikhanov Kokshetau State University, Kokshetau 020000, Kazakhstan.ORCID 0000-0003-0079-4755 Ubaidilla M DatkhayevSchool of Pharmacy, Asfendiyarov Kazakh National Medical University, Almaty 050000, Kazakhstan.ORCID 0000-0002-2322-220X Olzhas T SeilkhanovThe Laboratory of Engineering Profile of NMR Spectroscopy, Sh. Ualikhanov Kokshetau State University, Kokshetau 020000, Kazakhstan.ORCID 0000-0002-2322-8863 Funding
Research funding for this project was provided by the Committee of Science of the Ministry of Science and Higher Education of the Republic of Kazakhstan AP26198287
6 · The paper itselfAbstract
The cyclic adamantane framework possesses unique properties such as bulkiness, symmetry, and high lipophilicity. Research aimed at discovering new pharmaceutical agents within the adamantane series continues. In the present work, a targeted modification was carried out to combine two pharmacophore fragments-adamantane and piperidine-within a single molecule. Based on a series of
Indexed as
AdamantaneAnti-Bacterial AgentsAntifungal AgentsAnti-Infective AgentsPiperidinesCandida albicansHumansMicrobial Sensitivity TestsMolecular StructureStaphylococcus aureusStructure-Activity RelationshipAdamantaneAnti-Bacterial AgentsAntifungal AgentsAnti-Infective AgentsPiperidinesadamantancarboxylatesantifungal activityantimicrobial activitycytotoxicitypiperidines
Identifiers
PMID41683416
PMCPMC12899892
What OpenQuestion holds
Textmetadata
LicenceCC BY
Read underepoch 390