Evidence map›Paper›PMID 41683258›Full record

ArticleNutrients2026

Effects of Marathon Running on Skin and Plasma Carotenoids in Endurance Runners.

Damon Joyner, Tracy M Covey, Leigh Komperda, Margarita Lopez, Saori Hanaki, Bryan Dowdell, Stacie Wing-Gaia, Qi Jin, Jamie Stein, David Aguilar

Abstract read
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In one paragraph

Article in Nutrients, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Damon JoynerDepartment of Exercise and Nutrition Sciences, Weber State University, 1435 Village Dr., Ogden, UT 84403, USA.
Tracy M CoveyDepartment of Chemistry and Biochemistry, Weber State University, 1415 Edvalson St., Ogden, UT 84403, USA.ORCID 0000-0002-4976-2730
Leigh KomperdaDepartment of Chemistry and Biochemistry, Weber State University, 1415 Edvalson St., Ogden, UT 84403, USA.
Margarita LopezDepartment of Exercise and Nutrition Sciences, Weber State University, 1435 Village Dr., Ogden, UT 84403, USA.
Saori HanakiDepartment of Exercise and Nutrition Sciences, Weber State University, 1435 Village Dr., Ogden, UT 84403, USA.ORCID 0000-0001-8315-810X
Bryan DowdellDepartment of Exercise and Nutrition Sciences, Weber State University, 1435 Village Dr., Ogden, UT 84403, USA.
Stacie Wing-GaiaDepartment of Exercise and Nutrition Sciences, Weber State University, 1435 Village Dr., Ogden, UT 84403, USA.
Qi JinDepartment of Exercise and Nutrition Sciences, Weber State University, 1435 Village Dr., Ogden, UT 84403, USA.
Jamie SteinDepartment of Exercise and Nutrition Sciences, Weber State University, 1435 Village Dr., Ogden, UT 84403, USA.
David AguilarDepartment of Exercise and Nutrition Sciences, Weber State University, 1435 Village Dr., Ogden, UT 84403, USA.

Funding

Weber State University Ambrose Amos Shaw Endowed Chair Award
6 · The paper itself

Abstract

BACKGROUND/

objectivesCarotenoids are pigmented phytochemicals known for their antioxidant properties, known to protect against oxidative damage, especially in the context of intense exercise. The purpose of this paper was to observe and analyze the short-term effects of running a full marathon on skin and plasma carotenoid levels in endurance runners.

methodsThis study recruited 24 healthy endurance runners (12 male, 12 female; mean age 37 years) registered for a 26.2-mile marathon. Skin carotenoid (SC) measures were taken via reflection spectroscopy, and plasma carotenoid concentrations (lycopene and β-carotene) were assessed via HPLC at three time points: pre-race, immediately post-race, and 48 h post-race. Changes across time were analyzed using repeated-measures ANOVA.

resultsSkin carotenoid levels significantly changed over time, dropping from pre-race to post-race (

conclusionsThe significant acute depletion of SC levels immediately following the marathon reflects the rapid utilization of these dermal antioxidants in response to the high oxidative stress generated by intense exercise. The elevation in plasma lycopene may reflect hemoconcentration resulting from intense activity and possible mobilization from tissue stores. The rapid rebound and overshoot in SC levels 48 h after the race are consistent with a recovery pattern of dermal carotenoid levels following acute depletion.

Indexed as

CarotenoidsMarathon RunningPhysical EnduranceRunningSkinAdultAntioxidantsbeta CaroteneFemaleHumansLycopeneMaleAntioxidantsbeta CaroteneCarotenoidsLycopenebeta-carotenecarotenoidsexerciselycopenemarathonoxidative stressphytochemicalsrunners

Identifiers

PMID41683258
PMCPMC12899393

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.