Evidence map›Paper›PMID 41683141›Full record

ArticleFoods (Basel, Switzerland)2026

Antidepressant Mechanisms of L-Theanine in Tea Based on Network Pharmacology, Molecular Docking, and Molecular Dynamics Simulations.

Yutao Shi, Yuan Yang, Xi Cheng, Canyang Huang, Yan Huang, Li Lu, Shuyan Wang, Yucheng Zheng, Feiquan Wang, Bo Zhang and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Foods (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Yutao ShiTea Science Research Institute, Tea Engineering Research Center of Fujian Higher Education, College of Tea and Food Sciences, Wuyi University, Wuyishan 354300, China.ORCID 0000-0003-2560-7143
Yuan YangTea Science Research Institute, Tea Engineering Research Center of Fujian Higher Education, College of Tea and Food Sciences, Wuyi University, Wuyishan 354300, China.
Xi ChengTea Science Research Institute, Tea Engineering Research Center of Fujian Higher Education, College of Tea and Food Sciences, Wuyi University, Wuyishan 354300, China.
Canyang HuangTea Science Research Institute, Tea Engineering Research Center of Fujian Higher Education, College of Tea and Food Sciences, Wuyi University, Wuyishan 354300, China.
Yan HuangTea Science Research Institute, Tea Engineering Research Center of Fujian Higher Education, College of Tea and Food Sciences, Wuyi University, Wuyishan 354300, China.
Li LuTea Science Research Institute, Tea Engineering Research Center of Fujian Higher Education, College of Tea and Food Sciences, Wuyi University, Wuyishan 354300, China.
Shuyan WangTea Science Research Institute, Tea Engineering Research Center of Fujian Higher Education, College of Tea and Food Sciences, Wuyi University, Wuyishan 354300, China.
Yucheng ZhengTea Science Research Institute, Tea Engineering Research Center of Fujian Higher Education, College of Tea and Food Sciences, Wuyi University, Wuyishan 354300, China.
Feiquan WangTea Science Research Institute, Tea Engineering Research Center of Fujian Higher Education, College of Tea and Food Sciences, Wuyi University, Wuyishan 354300, China.ORCID 0009-0003-1337-4052
Bo ZhangTea Science Research Institute, Tea Engineering Research Center of Fujian Higher Education, College of Tea and Food Sciences, Wuyi University, Wuyishan 354300, China.
Shulin ZhengTea Science Research Institute, Tea Engineering Research Center of Fujian Higher Education, College of Tea and Food Sciences, Wuyi University, Wuyishan 354300, China.

Funding

Fujian Provincial Science and Technology Plan Guiding Project No. 2022N0030Fujian Provincial Undergraduate Innovation and Entrepreneurship Training Program No. S202410397037Nanping Science and Technology Commissioner-Oriented Industry Technology Innovation Joint Funding Program No. N2023Z006Natural Science Foundation of Fujian Province (General program) No.2023J011048Research Development Fund of Wuyi University No.2020J01404-2, 2020R1008002Special Fund for Improving the Running Level of Institutions of Higher Education in Fujian Province Fujian Provincial Department of Finance and Department of Education [2022] No.77
6 · The paper itself

Abstract

L-theanine is a bioactive non-protein amino acid predominantly derived from tea plants (

Indexed as

binding free energyhub targetsprotein–protein interaction (PPI)synaptic transmissiontarget prediction

Identifiers

PMID41683141
PMCPMC12897157

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.