Evidence map›Paper›PMID 41683076›Full record

ArticleFoods (Basel, Switzerland)2026

Multi-Pathway Mechanisms of Beef in Ameliorating Spleen Deficiency Syndrome: Insights from Digestive Function, Immunity, and Gut Microbiota.

Ying Zhang, Ang Ru, Xinghui Wang, Ke Wang, Xueyuan Bai, Xinjun Zhang, Chaozhi Zhu, Gaiming Zhao

Abstract read
In one paragraph

Article in Foods (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ying ZhangHenan Key Lab of Meat Processing and Quality Safety Control, Henan Agricultural University, Zhengzhou 450002, China.
Ang RuHenan Key Lab of Meat Processing and Quality Safety Control, Henan Agricultural University, Zhengzhou 450002, China.
Xinghui WangHenan Key Lab of Meat Processing and Quality Safety Control, Henan Agricultural University, Zhengzhou 450002, China.
Ke WangHenan Key Lab of Meat Processing and Quality Safety Control, Henan Agricultural University, Zhengzhou 450002, China.ORCID 0000-0001-6636-8041
Xueyuan BaiHenan Key Lab of Meat Processing and Quality Safety Control, Henan Agricultural University, Zhengzhou 450002, China.
Xinjun ZhangNingxia Xiahua Meat Food Co., Ltd., Zhongwei 755000, China.
Chaozhi ZhuHenan Key Lab of Meat Processing and Quality Safety Control, Henan Agricultural University, Zhengzhou 450002, China.
Gaiming ZhaoHenan Key Lab of Meat Processing and Quality Safety Control, Henan Agricultural University, Zhengzhou 450002, China.ORCID 0000-0002-4538-3186

Funding

Hebei modern agricultural industrial technology system beef cattle industry innovation team construction project HBCT2023190204Key Research and Development Program of Ningxia Hui Autonomous Region: "Research and Application of Key Technologies for Prefabricated Processing of Beef Specialty Products" 2024BBF02020the National Beef Cattle Industrial Technology System No. CARS-37
6 · The paper itself

Abstract

Beef and yam are valued as functional foods, yet their synergistic effects on gastrointestinal health and immunity remain underexplored. This study investigated the effects of beef and yam on the spleen and stomach. In the present study, a rat model of spleen deficiency was established by poor diet and exhaustive swimming. The weight, food intake, gastrointestinal and immune indexes, and the intestinal flora of the rats were examined. The results showed that the levels of gastrin, motilin, and four cytokines improved. Specifically, the beef group exhibited marked recovery in gastrointestinal hormones, with serum gastrin and motilin levels increasing to approximately 60 pg/mL and 70 pg/mL, respectively, close to the normal control levels, and significantly higher than the model group. The beef and yam effectively restored the balance of intestinal flora, which significantly increased the diversity of intestinal microorganisms. In addition, the tissue structure of the spleen, stomach, small intestine, and colon was also effectively improved. Additionally, yam increased gut microbial diversity and optimized the microbial community structure, consequently enhancing the overall health status. This study elucidates the multi-pathway mechanisms by which beef and yam ameliorate spleen deficiency, providing a scientific basis for their application in functional foods.

Indexed as

beefChinese yamhealthy foodsmedicine food homologytonifying spleen

Identifiers

PMID41683076
PMCPMC12896656

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.