Evidence map›Paper›PMID 41683008›Full record

ArticleFoods (Basel, Switzerland)2026

Echinacea Purpurea Polysaccharides Alleviate DSS-Induced Colitis in Rats by Regulating Gut Microbiota and Short-Chain Fatty Acid Metabolism.

Cui Liu, Yongshi Lin, Xiaoxiao Du, Jiahui Mei, Kailun Xi, Yun Gao, Yuqing Li, Zongtao Zuo

Abstract read
In one paragraph

Article in Foods (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Cui LiuCollege of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China.ORCID 0000-0002-0609-0073
Yongshi LinCollege of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China.
Xiaoxiao DuCollege of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China.
Jiahui MeiCollege of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China.
Kailun XiCollege of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China.
Yun GaoCollege of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China.
Yuqing LiCollege of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China.
Zongtao ZuoCollege of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China.

Funding

National Natural Science Foundation of China 32273046
6 · The paper itself

Abstract

To investigate whether Echinacea purpurea polysaccharides (EPP) alleviate inflammatory bowel disease (IBD) by modulating gut microbiota, we utilized a mixed antibiotic (ABX)-induced gut dysbiosis model and a co-housing model in rats. ABX treatment severely reduces microbial richness and functional diversity, decreasing SCFA-producing bacteria and impairing the anti-inflammatory effect of SCFA-mediated EPP. Without ABX, EPP significantly ameliorates IBD symptoms and colonic pathology damage in rats, reduces the levels of pro-inflammatory cytokines (IL-1β, IL-6, TNF-α) (

Indexed as

Echinacea purpurea polysaccharidegut microbiotainflammatory bowel diseaseshort-chain fatty acids

Identifiers

PMID41683008
PMCPMC12896625

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.