Evidence map›Paper›PMID 41682951›Full record

ArticleJournal of clinical medicine2026

Association Between Plasma and Urinary Reduced Thiols in Essential Hypertension: Evidence from a Paired Observational Study.

Antón Cruces-Sande, Néstor Vázquez-Agra, Óscar Seoane-Casqueiro, Emma López-Prado, Estefanía Méndez-Álvarez, Ramón Soto-Otero, Antonio Pose-Reino, Álvaro Hermida-Ameijeiras

Registry-linked trialAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of clinical medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06325800 (Multimodal Vascular Phenotyping and Target-Organ Damage Using Vascular Imaging, Glyco-Oxidative Biomarkers, and Photoplethysmography in Adults at Increased Cardiovascular Risk), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06325800 recruitingnot on this map

Multimodal Vascular Phenotyping and Target-Organ Damage Using Vascular Imaging, Glyco-Oxidative Biomarkers, and Photoplethysmography in Adults at Increased Cardiovascular Risk: The GlycOxiTOD Observational Registry

Typeobservational_patient_registrySponsorComplejo Hospitalario Universitario de SantiagoRan2024 to 2035Enrolled1,000ConditionsHypertension, Target Organ Damage, Heart Disease Risk Factors, Vascular StiffnessArmsMultimodal Cardiovascular Phenotyping
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Antón Cruces-SandeLaboratory of Neurochemistry, Department of Biochemistry and Molecular Biology, Faculty of Medicine, University of Santiago de Compostela, 15782 Santiago de Compostela, A Coruña, Spain.ORCID 0000-0002-8661-8471
Néstor Vázquez-AgraHealth Research Institute of Santiago de Compostela (IDIS), Travesía da Choupana s/n, 15706 Santiago de Compostela, A Coruña, Spain.ORCID 0000-0003-3227-8990
Óscar Seoane-CasqueiroHealth Research Institute of Santiago de Compostela (IDIS), Travesía da Choupana s/n, 15706 Santiago de Compostela, A Coruña, Spain.
Emma López-PradoSchool of Industrial Engineering, University of Vigo (UVigo), 36310 Vigo, Pontevedra, Spain.
Estefanía Méndez-ÁlvarezLaboratory of Neurochemistry, Department of Biochemistry and Molecular Biology, Faculty of Medicine, University of Santiago de Compostela, 15782 Santiago de Compostela, A Coruña, Spain.ORCID 0000-0002-9121-2441
Ramón Soto-OteroLaboratory of Neurochemistry, Department of Biochemistry and Molecular Biology, Faculty of Medicine, University of Santiago de Compostela, 15782 Santiago de Compostela, A Coruña, Spain.ORCID 0000-0003-0079-0279
Antonio Pose-ReinoHealth Research Institute of Santiago de Compostela (IDIS), Travesía da Choupana s/n, 15706 Santiago de Compostela, A Coruña, Spain.
Álvaro Hermida-AmeijeirasHealth Research Institute of Santiago de Compostela (IDIS), Travesía da Choupana s/n, 15706 Santiago de Compostela, A Coruña, Spain.ORCID 0000-0003-3757-262X

Funding

Health Research Institute of Santiago de Compostela Postdoctoral fellowship from the Health Research Institute of Santiago de Compostela (IDIS)Instituto de Salud Carlos III CM23/00018
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

cardiovascular riskessential hypertensionnon-invasive assessmentoxidative stressplasma biomarkersredox statusthiolsurine biomarkers

Identifiers

PMID41682951
PMCPMC12898165

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.