Evidence map›Paper›PMID 41682783›Full record

ReviewJournal of clinical medicine2026

Neuroblastoma in Childhood: Biological Insights, Risk Stratification, and Advances in Multimodal Therapy.

Amina De Bona, Martina Barbieri, Nicole Rinaldi, Susanna Esposito

Abstract readReview
In one paragraph

Review in Journal of clinical medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. A comprehensive survey of genetic variants in neuroblastoma.Journal, genetic engineering & biotechnology · 2026
    Article
  2. Article
  3. Revista de neurologia · 2026
    Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Amina De BonaPediatric Clinic, Department of Medicine and Surgery, University of Parma, 43126 Parma, Italy.
Martina BarbieriPediatric Clinic, Department of Medicine and Surgery, University of Parma, 43126 Parma, Italy.ORCID 0009-0003-7981-9982
Nicole RinaldiPediatric Clinic, Department of Medicine and Surgery, University of Parma, 43126 Parma, Italy.ORCID 0009-0004-2918-6408
Susanna EspositoPediatric Clinic, Department of Medicine and Surgery, University of Parma, 43126 Parma, Italy.ORCID 0000-0003-4103-2837

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neuroblastoma is the most common extracranial solid tumor of childhood and remains a leading cause of cancer-related mortality in pediatric patients. Characterized by marked clinical and biological heterogeneity, the disease ranges from spontaneously regressing tumors in infants to highly aggressive, treatment-resistant malignancies in older children. Advances in molecular biology and genomics have significantly improved understanding of neuroblastoma pathogenesis, revealing the critical role of genetic and epigenetic alterations-such as

Indexed as

immunotherapymolecular profilingMYCN amplificationneuroblastomaprecision medicinerisk stratificationtargeted therapy

Identifiers

PMID41682783
PMCPMC12898582

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.