Evaluation of Viral Collection Efficiency with Antibody-Modified Magnetic Particles by Polymerase Chain Reaction Assay.

Masato Yasuura, Hiroki Ashiba, Ken-Ichi Nomura

Abstract read

In one paragraph

Article in Sensors (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Masato YasuuraSensing Technology Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), Central 5, 1-1-1 Higashi, Tsukuba 305-8565, Ibaraki, Japan.ORCID 0000-0003-2334-8088

Hiroki AshibaSensing Technology Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), Central 5, 1-1-1 Higashi, Tsukuba 305-8565, Ibaraki, Japan.ORCID 0000-0002-8764-8357

Ken-Ichi NomuraSensing Technology Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), Central 5, 1-1-1 Higashi, Tsukuba 305-8565, Ibaraki, Japan.ORCID 0000-0001-9459-1101

Funding

Japan Society for the Promotion of Science 21H01466New Energy and Industrial Technology Development Organization JPNP19005

6 · The paper itself

Abstract

Polymerase chain reaction (PCR) is the primary method for virus detection; however, its complex preprocessing has prompted research into simpler immunoassay-based approaches. Among these, techniques using antibody-modified magnetic particles, exemplified by digital ELISA, provide ultra-high sensitivity comparable to PCR by efficiently capturing trace viruses and enabling concentration, washing, and transfer to microreactors. In this study, we evaluated the virus capture efficiency of antibody-modified magnetic particles based on quantitative PCR (qPCR). Influenza A virus (H1N1/A/Puerto Rico/8/1934) was tested with 1 μm magnetic beads modified with HA1 antibodies. As quantification becomes unreliable and difficult in an extremely low-concentration range near the detection limit of qPCR, low-concentration viral suspensions (10

Indexed as

AntibodiesInfluenza A Virus, H1N1 SubtypePolymerase Chain ReactionEnzyme-Linked Immunosorbent AssayHumansAntibodiesbead-based assaydigital assayhighly sensitive detectionimmunoassayinfluenza virusrapid detection

Identifiers

PMID41682535

DOI10.3390/s26031019

PMCPMC12900115

What OpenQuestion holds

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LicenceCC BY

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.