Simultaneous Down-Regulation of Intracellular hTERT and GPX4 mRNA Using MnO

Yixin Miao, Tao Zhou, Qinghong Ji, Min Hong

Abstract read

In one paragraph

Article in Sensors (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yixin MiaoSchool of Chemistry and Chemical Engineering, Liaocheng University, Liaocheng 252059, China.

Tao ZhouSchool of Chemistry and Chemical Engineering, Liaocheng University, Liaocheng 252059, China.

Qinghong JiSchool of Chemistry and Chemical Engineering, Liaocheng University, Liaocheng 252059, China.

Min HongSchool of Chemistry and Chemical Engineering, Liaocheng University, Liaocheng 252059, China.ORCID 0000-0001-8406-0323

Funding

Natural Science Foundation of Shandong Province ZR2015BM024

6 · The paper itself

Abstract

Cancer remains a leading global cause of death, with conventional treatments often limited by toxicity and recurrence. Recent advances in gene therapy and nanodrug delivery offer new avenues for precision oncology. Human telomerase reverse transcriptase (hTERT) and glutathione peroxidase 4 (GPX4) are overexpressed in many cancers and linked to apoptosis and ferroptosis, respectively. Here, we developed a manganese dioxide nanosheet (MnO

Indexed as

Down-RegulationManganese CompoundsNanostructuresNeoplasmsOxidesPhospholipid Hydroperoxide Glutathione PeroxidaseRNA, MessengerTelomeraseApoptosisCell DeathCell Line, TumorCell ProliferationGlutathioneHumansOligonucleotides, AntisenseGlutathioneManganese Compoundsmanganese dioxideOligonucleotides, AntisenseOxidesPhospholipid Hydroperoxide Glutathione PeroxidaseRNA, MessengerTelomeraseTERT protein, humangene silencingGPX4hTERTinhibiting cancer cell proliferationmanganese dioxide nanosheet probe

Identifiers

PMID41682351

DOI10.3390/s26030836

PMCPMC12899576

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.