Evidence map›Paper›PMID 41681970›Full record

ReviewCancers2026

Boron Neutron Capture Therapy: A Technology-Driven Renaissance.

Dandan Zheng, Guang Han, Olga Dona Maria Lemus, Alexander Podgorsak, Matthew Webster, Fiona Li, Yuwei Zhou, Hyunuk Jung, Jihyung Yoon

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Cancers, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Dandan ZhengDepartment of Radiation Oncology, University of Rochester, Rochester, NY 14627, USA.ORCID 0000-0003-2259-1633
Guang HanDepartment of Radiation Oncology, Hubei Cancer Hospital, Huazhong University of Science and Technology, Wuhan 430079, China.
Olga Dona Maria LemusDepartment of Radiation Oncology, University of Miami, Coral Gables, FL 33146, USA.
Alexander PodgorsakDepartment of Radiation Oncology, University of Rochester, Rochester, NY 14627, USA.
Matthew WebsterDepartment of Radiation Oncology, University of Rochester, Rochester, NY 14627, USA.ORCID 0009-0008-4306-5441
Fiona LiDepartment of Radiation Oncology, University of Rochester, Rochester, NY 14627, USA.ORCID 0000-0002-2423-6953
Yuwei ZhouDepartment of Radiation Oncology, University of Rochester, Rochester, NY 14627, USA.
Hyunuk JungDepartment of Radiation Oncology, University of Rochester, Rochester, NY 14627, USA.ORCID 0000-0002-2004-6925
Jihyung YoonDepartment of Radiation Oncology, University of Rochester, Rochester, NY 14627, USA.ORCID 0000-0001-8588-3380

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Boron neutron capture therapy (BNCT) is experiencing a global resurgence driven by advances in boron pharmacology, accelerator-based neutron sources, and molecular imaging-guided theranostics. BNCT produces high linear energy transfer particles with micrometer-range energy deposition, enabling cell-selective irradiation confined to boron-enriched tumor cells in a geometrically targeted region by the neutron beam. This mechanism offers the potential for exceptionally high therapeutic ratios, provided two core requirements are met: sufficient differential tumor uptake of

Indexed as

BNCTboronneutronpersonalized therapyprecision medicinetheranostics

Identifiers

PMID41681970
PMCPMC12896740

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.