The IAOx-Dependent IAA Biosynthesis Pathway: Acquired Insights, Paradigm Shifts, and Unresolved Questions.

Ming-Kun Ma, Verena Kriechbaumer, Dong-Wei Di

Abstract readReview

In one paragraph

Review in Plants (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

Recent Advances and Future Perspectives in Plant Auxin Biology.Plants (Basel, Switzerland) · 2026
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Ming-Kun MaInstitute of Agricultural Resources and Environment, Sichuan Academy of Agricultural Sciences, Chengdu 610066, China.

Verena KriechbaumerSchool of Biological and Medical Sciences, Faculty of Health, Science and Technology, Oxford Brookes University, Oxford OX3 0BP, UK.ORCID 0000-0003-3782-5834

Dong-Wei DiState Key Laboratory of Soil and Sustainable Agriculture, Institute of Soil Science, Chinese Academy of Sciences, Nanjing 210008, China.ORCID 0000-0003-4453-6862

Funding

Field Frontier Program of the Institute of Soil Science ISSAS2412Natural Science Foundation of Jiangsu Province BK20240214

6 · The paper itself

Abstract

The auxin indole-3-acetic acid (IAA) is essential for plant growth and stress adaptation. Its biosynthesis via the indole-3-acetaldoxime (IAOx) pathway has recently undergone a paradigm shift. Recent genetic and metabolomic studies have fundamentally revised the indole-3-acetaldoxime (IAOx) pathway from a linear route (IAOx→IAN→IAM→IAA) to a dynamic network. This review synthesizes this paradigm shift by integrating evidence from key Arabidopsis studies. Crucially, mutants disrupting multiple downstream enzyme families fail to block IAA overproduction in the IAOx-accumulating

Indexed as

auxin biosynthesisgrowth-defense trade-offindole-3-acetaldoximeindole-3-acetamideindole-3-acetonitrile

Identifiers

PMID41681602

DOI10.3390/plants15030436

PMCPMC12899392

What OpenQuestion holds

Textmetadata

LicenceCC BY

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.