Evidence map›Paper›PMID 41681445›Full record

ArticleAnimals : an open access journal from MDPI2026

Study on the Effect of N-Carbamylglutamate (NCG) on Reproductive Performance and Regulation Mechanism of Primary Lake Sheep.

Tianli Gao, Chunyang Li, Juanshan Zheng, Yingpai Zhaxi, Yuan Cai, Rongxin Zang, Huixia Liu, Yanmei Yang, Sai Li, Xiaodi Shi and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Animals : an open access journal from MDPI, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Gut Microbiota-Derived Short-Chain Fatty Acids Driven by N-Carbamylglutamate Alleviates Premature Ovarian Failure Through Suppressing Ferroptosis.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Tianli GaoSchool of Life Science and Engineering, Northwest Minzu University, Lanzhou 730030, China.
Chunyang LiSchool of Life Science and Engineering, Northwest Minzu University, Lanzhou 730030, China.
Juanshan ZhengSchool of Life Science and Engineering, Northwest Minzu University, Lanzhou 730030, China.
Yingpai ZhaxiSchool of Life Science and Engineering, Northwest Minzu University, Lanzhou 730030, China.
Yuan CaiSchool of Life Science and Engineering, Northwest Minzu University, Lanzhou 730030, China.
Rongxin ZangSchool of Life Science and Engineering, Northwest Minzu University, Lanzhou 730030, China.
Huixia LiuSchool of Life Science and Engineering, Northwest Minzu University, Lanzhou 730030, China.
Yanmei YangSchool of Life Science and Engineering, Northwest Minzu University, Lanzhou 730030, China.
Sai LiSchool of Life Science and Engineering, Northwest Minzu University, Lanzhou 730030, China.
Xiaodi ShiSchool of Life Science and Engineering, Northwest Minzu University, Lanzhou 730030, China.
Chen HuangSchool of Life Science and Engineering, Northwest Minzu University, Lanzhou 730030, China.

Funding

Central University Basic Research Fund 31920240045Lanzhou Science and Technology Plan Project 2021-1-171The 14th Five-Year Plan Key R&D Program 2024YFD1301002
6 · The paper itself

Abstract

The aim of this study was to investigate the effects of dietary supplementation with 0.11% N-carbamylglutamate (NCG) during early pregnancy (0-90 days) on reproductive performance and fetal development, and to elucidate the underlying placental regulatory mechanisms in primiparous Hu sheep. Twenty-two 10-month-old sexually mature primiparous Hu sheep meeting the mating criteria were randomly assigned to two groups. The control group was fed a basal diet, while the NCG group received the basal diet supplemented with 0.11% NCG, with both feeding regimens maintained for 90 days. By measuring uterine and fetal growth indices, maternal plasma biochemical parameters, and amino acid levels, as well as assessing cotyledon indices and observing cotyledon morphology and histological structure, basic data related to placental function and fetal growth in pregnant ewes was collected. Combined with transcriptomic sequencing of maternal placental tissue, the mechanism by which NCG influences placental function and fetal growth and development in pregnant ewes was further investigated. The supplementation of NCG could increase the number of fetuses, total weight of fetuses, the number of corpus luteum and the ratio of fetuses to corpus luteum, but the difference was not significant (

Indexed as

fetal developmentHu sheepN-carbamylglutamate (NCG)reproductive performancetranscriptomic sequencing

Identifiers

PMID41681445
PMCPMC12896565

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.