Evidence map›Paper›PMID 41681438›Full record

ReviewAnimals : an open access journal from MDPI2026

Swine Enteric Coronaviruses: An Updated Overview of Epidemiology, Diagnosis, Prevention, and Control.

Yassein M Ibrahim, Can Liu, Yuandi Yu, Liu Yang, Qianlin Chen, Wenjie Ma, Gebremeskel Mamu Werid, Shaomei Li, Jie Luo, Shengbin Gao and 3 more

Abstract readReview
In one paragraph

Review in Animals : an open access journal from MDPI, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Yassein M IbrahimChongqing Academy of Animal Science, Chongqing 402460, China.ORCID 0000-0002-4167-4998
Can LiuChongqing Academy of Animal Science, Chongqing 402460, China.
Yuandi YuChongqing Academy of Animal Science, Chongqing 402460, China.
Liu YangChongqing Academy of Animal Science, Chongqing 402460, China.
Qianlin ChenChongqing Academy of Animal Science, Chongqing 402460, China.
Wenjie MaChongqing Academy of Animal Science, Chongqing 402460, China.
Gebremeskel Mamu WeridDavies Livestock Research Centre, School of Animal & Veterinary Sciences, University of Adelaide, Rose Worthy Campus, Rose Worthy, Adelaide 5371, Australia.ORCID 0000-0002-3189-1470
Shaomei LiChongqing Academy of Animal Science, Chongqing 402460, China.
Jie LuoChongqing Academy of Animal Science, Chongqing 402460, China.
Shengbin GaoChina Center of Animal Health and Epidemiology, Qingdao 266000, China.
Suhui ZhangChongqing Academy of Animal Science, Chongqing 402460, China.
Lizhi FuChongqing Academy of Animal Science, Chongqing 402460, China.
Yue WangNational Center of Technology Innovation for Pigs, Chongqing 402460, China.ORCID 0000-0003-1575-3569

Funding

this work was supported by grants from the National Center of Technology Innovation for Pigs (NCTIP-XD/B19); the Chongqing Talent plan "contract system" project (cstc2022ycjh-bgzxm0183 and 22509C); the Sichuan Provincial Regional Innovation Cooperation Pr (cstc2022ycjh-bgzxm0183 and 22509C) and (2024YFHZ0110)
6 · The paper itself

Abstract

Swine enteric coronaviruses (SECoVs), including transmissible gastroenteritis virus (TGEV), porcine epidemic diarrhea virus (PEDV), porcine deltacoronavirus (PDCoV), and swine acute diarrhea syndrome coronavirus (SADS-CoV), are major enteric pathogens causing severe diarrhea, dehydration, high neonatal mortality, and substantial global economic losses. Rapid viral evolution and recombination continually generate antigenically diverse variants that limit cross-protection and undermine vaccine efficacy, particularly for PEDV genogroup II strains that now dominate worldwide circulation. This review synthesizes current knowledge on epidemiology, diagnostic innovations, and emerging vaccine platforms, with emphasis on advances since 2022. Recent progress includes molecular surveillance tools, rapid point-of-care diagnostics, and next-generation vaccine technologies such as mRNA-based and virus-like particle platforms. However, significant knowledge gaps persist regarding viral evolution dynamics, co-infection synergies, and zoonotic spillover potential, particularly following documented human infections with PDCoV. Effective long-term control requires integrated genomic surveillance, strengthened farm-level biosecurity, rationally designed multivalent vaccines targeting conserved epitopes, and harmonized international surveillance systems to reduce outbreak risk and enhance pandemic preparedness at the human-animal interface.

Indexed as

biosecuritycross-species transmissiondiagnosticsepidemiologyswine enteric coronavirusesvaccines

Identifiers

PMID41681438
PMCPMC12897436

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.