Band Neutrophils Are Observed in Dogs Undergoing Multiagent Chemotherapy Including Vincristine.

Caitlin N Eliason, Steven J Pierce, Alison Masyr

Abstract read

In one paragraph

Article in Animals : an open access journal from MDPI, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Caitlin N EliasonDepartment of Small Animal Clinical Sciences, College of Veterinary Medicine, Michigan State University, East Lansing, MI 48824, USA.ORCID 0009-0002-7075-6172

Steven J PierceCenter for Statistical Training and Consulting (CSTAT), Michigan State University, East Lansing, MI 48824, USA.ORCID 0000-0002-0679-3019

Alison MasyrDepartment of Small Animal Clinical Sciences, College of Veterinary Medicine, Michigan State University, East Lansing, MI 48824, USA.ORCID 0009-0003-6584-2524

Funding

Start up funds Not applicable

6 · The paper itself

Abstract

Chemotherapy is known to cause significant neutropenia, though concomitant left shift (also known as bandemia) has yet to be documented in dogs. The objective of this study is to assess the prevalence of band neutrophil elevation in dogs undergoing multiagent chemotherapy and identify factors influencing bandemia development. Medical records were retrospectively reviewed between 2018 and 2022 for dogs that started multiagent chemotherapy with at least one follow-up visit. Records were analyzed for body surface area (BSA), white blood cell count, segmented neutrophil count, band neutrophil count, and the previously administered chemotherapy drug (vincristine, cyclophosphamide, or doxorubicin). A generalized linear mixed model was used for statistical analysis. Ninety dogs with 530 nadir complete blood counts (CBCs) were identified. Band neutrophils were present in 20.2% of nadir CBCs, and increased band neutrophils occurred in 13.6%. Smaller BSA was associated with higher bandemia prevalence. Bandemia prevalence was 6% higher after vincristine (Risk Difference, 95% CI = [1%, 11%],

Indexed as

chemotherapydogsneutrophil band cellsneutrophilsvincristine

Identifiers

PMID41681415

DOI10.3390/ani16030434

PMCPMC12897173

What OpenQuestion holds

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LicenceCC BY

Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.