Evidence map›Paper›PMID 41681141›Full record

ArticleMaterials (Basel, Switzerland)2026

Gadolinium-Doped Hydroxyapatite Nanoparticles Functionalized with Curcumin and Folic Acid: Structural Insights and Magnetic Behavior for Theranostic Applications.

Jéssica P N Marinho, Luísa A F Vieira, André F Oliveira, Aloísio M Garcia, Monica E B Guarin, João Batista S Barbosa, Yan F X Ladeira, Adolfo H M Silva, Edésia M B de Sousa

Abstract read
In one paragraph

Article in Materials (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jéssica P N MarinhoCentro de Desenvolvimento da Tecnologia Nuclear (CDTN), Belo Horizonte 31270-901, MG, Brazil.ORCID 0000-0002-1717-6323
Luísa A F VieiraCentro de Desenvolvimento da Tecnologia Nuclear (CDTN), Belo Horizonte 31270-901, MG, Brazil.
André F OliveiraCentro de Desenvolvimento da Tecnologia Nuclear (CDTN), Belo Horizonte 31270-901, MG, Brazil.ORCID 0000-0002-7201-4650
Aloísio M GarciaCentro de Desenvolvimento da Tecnologia Nuclear (CDTN), Belo Horizonte 31270-901, MG, Brazil.
Monica E B GuarinCentro de Desenvolvimento da Tecnologia Nuclear (CDTN), Belo Horizonte 31270-901, MG, Brazil.ORCID 0000-0001-7731-2537
João Batista S BarbosaCentro de Desenvolvimento da Tecnologia Nuclear (CDTN), Belo Horizonte 31270-901, MG, Brazil.
Yan F X LadeiraDepartamento de Química, Universidade Federal de Minas Gerais (UFMG), Belo Horizonte 31270-901, MG, Brazil.
Adolfo H M SilvaDepartamento de Química, Universidade Federal de Minas Gerais (UFMG), Belo Horizonte 31270-901, MG, Brazil.ORCID 0000-0002-3344-4084
Edésia M B de SousaCentro de Desenvolvimento da Tecnologia Nuclear (CDTN), Belo Horizonte 31270-901, MG, Brazil.ORCID 0000-0002-6317-4054

Funding

Financiadora de Estudos e Projetos 01.22.0143.01Fundação de Amparo à Pesquisa do Estado de Minas Gerais APQ-01987-23 and APD-00437-25National Council for Scientific and Technological Development 304061/2022-0
6 · The paper itself

Abstract

Gadolinium-doped hydroxyapatite nanoparticles (HapGd NPs) have emerged as promising multifunctional platforms for biomedical applications due to their unique combination of biocompatibility, structural tunability, and magnetic responsiveness. In this work, HapGd nanoparticles were synthesized using a microwave-assisted method and subsequently functionalized with curcumin and folic acid to enhance therapeutic efficiency and selective targeting. The synthesized nanostructures were characterized using various techniques, including X-ray diffraction (XRD), transmission electron microscopy (TEM), Fourier-transform infrared spectroscopy (FTIR), thermogravimetric analysis (TGA), vibrating sample magnetometry (VSM), and relaxometry. Structural analyses revealed successful incorporation of Gd

Indexed as

curcumin functionalizationfolic acid targetinggadolinium dopinghydroxyapatite nanoparticlesmicrowave-assisted synthesistheranostic nanomaterials

Identifiers

PMID41681141
PMCPMC12898340

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.