Evidence map›Paper›PMID 41681082›Full record

ArticleDevelopmental medicine and child neurology2026

Long-term neurological and psychiatric outcomes after paediatric arterial ischaemic stroke and cerebral sinovenous thrombosis.

Jeanette Soenderlyng Springer, Søren Paaske Johnsen, Charlotte Olesen, Jan Brink Valentin, Ruta Tuckuviene

Abstract read
In one paragraph

Article in Developmental medicine and child neurology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Pediatric cerebral thrombosis is a lifelong neurodevelopmental condition.Developmental medicine and child neurology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jeanette Soenderlyng SpringerDanish Centre for Health Services Research, Department of Clinical Medicine, Aalborg University, Aalborg, Denmark.ORCID 0009-0004-5875-4590
Søren Paaske JohnsenDanish Centre for Health Services Research, Department of Clinical Medicine, Aalborg University, Aalborg, Denmark.
Charlotte OlesenDepartment of Paediatrics and Adolescent Medicine, Aarhus University Hospital, Aarhus, Denmark.
Jan Brink ValentinDanish Centre for Health Services Research, Department of Clinical Medicine, Aalborg University, Aalborg, Denmark.
Ruta TuckuvieneDepartment of Paediatrics and Adolescent Medicine, Juliane Marie Centre, Rigshospitalet, University Hospital of Copenhagen, Copenhagen, Denmark.

Funding

Aase og Ejnar Danielsens FondFamilien Hede Nielsens FondPeder Kristen Tøfting og Dagmar Tøfting´s FondSnedkermester Sophus Jacobsen og Hustru Astrid Jacobsens FondSpeciallæge Heinrich Kopps legatThe Department of Research, Education and Innovation at Aalborg University HospitalThe Paediatric Department at Aalborg University HospitalTømrermester Jørgen Holm og Hustru Elisa F. Hansens Mindelegat
6 · The paper itself

Abstract

aimTo examine long-term outcomes in children and adolescents after first-time arterial ischaemic stroke (AIS) or cerebral sinovenous thrombosis (CSVT).

methodPatients (0-18 years) diagnosed with a first-time cerebral thrombosis between 1994 and 2006 were followed until 2017 in this descriptive follow-up study. Patients were identified, and age- and sex-matched 1:10 with individuals from the general population. Data were extracted from national registries of patients. Outcomes included all-cause mortality, and hospital diagnoses of neurological and psychiatric disorders after cerebral thrombosis.

resultsA total of 251 patients with cerebral thrombosis were followed up for a median of 16 years (interquartile range 13 years 1 month-19 years 4 months). Cumulative all-cause mortality at 23 years 8 months was 11.4% (95% confidence interval [CI] 7.1-17.9). Hazard ratios indicated an increased risk of 64.0 times (95% CI 35.3-116.0) for cerebral palsy, 17.9 times (95% CI 10.2-31.5) for vision problems, and 4.1 times (95% CI 2.0-8.4) for being diagnosed with severe mental disorders during follow-up for those with previous cerebral thrombosis compared with the general population. The risk of morbidity was significantly increased following both AIS and CSVT.

interpretationChildren and adolescents experience a higher all-cause mortality and a high risk of neurological and psychiatric diagnoses after AIS or CSVT compared with the general population.

Indexed as

Cerebral PalsyIschemic StrokeMental DisordersNervous System DiseasesSinus Thrombosis, IntracranialAdolescentChildChild, PreschoolFemaleFollow-Up StudiesHumansInfantInfant, NewbornMaleRegistries

Identifiers

PMID41681082
PMCPMC13436706

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