ReviewEuropean journal of immunology2026
Distinguishing Features of ILC2s During Type 2 Immune Responses.
Review in European journal of immunology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Impacts of Environmental Pollutants on Innate Immunity: The Role of Group 2 Innate Lymphoid Cells.Clinical reviews in allergy & immunology · 2026Review
- Rapid and Highly Efficient CRISPR-Cas9 RNP Genome Editing in Primary ILC2s.European journal of immunology · 2026Article
- Distinguishing Features of ILC2s During Type 2 Immune Responses.European journal of immunology · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Innate lymphoid cells (ILCs) are innate immune cells populating many tissues early in ontogeny. ILCs and T cells share basic transcriptional programs, immune modules, and effector functions. This article focuses on ILC2s, a subset capable of producing an array of type 2 cytokines similar to T helper 2 (Th2) cells. While there is a striking overlap in effector functions between ILC2s and Th2 cells, we discuss the distinguishing features and nonredundant functions of ILC2s in homeostasis and during inflammation. These include the regulation of their effector functions, the kinetics of their response, and their spatial distribution. ILC2s interact with different cell types and maintain crosstalk with nonimmune cells, such as epithelial cells, stromal cells, and neurons. We review how neurons and epithelial cells trigger ILC2 responses and depend on ILC2-derived cytokines, leading to the concept that expulsion of many gut-dwelling nematodes is initiated and executed by the intestinal epithelium but strictly requires the type 2 immune response orchestrated by ILC2s.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.