Evidence map›Paper›PMID 41680905›Full record

ArticleBorderline personality disorder and emotion dysregulation2026

How specific are affective and attachment instability to adolescents with non-suicidal self-injury? A comparison with adolescents with major depression.

Annekatrin Steinhoff, Julian Koenig, Julia Blanke, Philip Santangelo, Ulrich Ebner-Priemer, Michael Kaess

Abstract read
In one paragraph

Article in Borderline personality disorder and emotion dysregulation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Annekatrin SteinhoffUniversity Hospital of Child and Adolescent Psychiatry and Psychotherapy, University of Bern, Bolligenstrasse 111, 3000, Bern, 60, Switzerland.
Julian KoenigDepartment of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, University Hospital Cologne, University of Cologne, Cologne, Germany.
Julia BlankeKinder- und Jugendpsychiatrische Institutsambulanz, Zentrum für Psychiatrie Calw, Klinikum Nordschwarzwald, Calw, Germany.
Philip SantangeloDepartment of Behavioural and Cognitive Sciences, University of Luxembourg, Esch-sur- Alzette, Luxembourg.
Ulrich Ebner-PriemerInstitute of Sport and Sports Science, Karlsruhe Institute of Technology, Karlsruhe, Germany.
Michael KaessUniversity Hospital of Child and Adolescent Psychiatry and Psychotherapy, University of Bern, Bolligenstrasse 111, 3000, Bern, 60, Switzerland. Michael.Kaess@upd.ch.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAffective and interpersonal instability are suggested to underlie adolescent non-suicidal self-injury (NSSI). However, previous research has not directly compared adolescents with NSSI to those with psychiatric conditions that are often, but not always, correlated with NSSI. We explored the specificity of affective and interpersonal instability to adolescent NSSI compared to depression.

methodsBased on a clinical sample of 70 adolescents (56 female and 14 male), we compared a group with NSSI (n = 50) with a clinical comparison group diagnosed with major depression and no engagement in NSSI (n = 20). We used high-frequency ecological momentary assessments (EMA) of affect and interpersonal attachment over four days. Mean affect and mean attachment as well as the root mean squares of successive differences (RMSSD) indicating instability of affect and attachment were calculated. The groups were compared using regression modeling.

resultsAdolescents with NSSI reported less positive affect and lower levels of attachment to their mothers and best friends than those with depression. Moreover, models adjusting for gender and mean affect and attachment, respectively, indicated that the NSSI group experienced more affective instability (b = 6.26, 95% CI = 0.79—11.73, p = 0.025). The two groups experienced similar average levels of attachment instability. Although there was no moderating effect of gender in the reported associations, the link between affective instability and NSSI was mainly driven by the male subsample, whereas low levels of attachment were associated with NSSI especially in females.

conclusionsAffective instability is especially high among adolescents with NSSI. When co-occurring with other disorders, NSSI may serve as an identifier of a patient’s particularly strong need for treatment aiming at affect stabilization.

Indexed as

AdolescentsAffective instabilityBorderline personality disorderEcological momentary assessmentNon-suicidal self-injury

Identifiers

PMID41680905
PMCPMC12997848

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.