Evidence map›Paper›PMID 41680802›Full record

ArticleBMC health services research2026

Early impacts of PEPFAR funding freeze on HIV service delivery in mid-Western Uganda.

Henry Zakumumpa, Alinaitwe Adolf, Jepchirchir Kiplagat, Felishana Cherop, Violet Bosire, Esther Buregyeya

Abstract read
In one paragraph

Article in BMC health services research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Henry ZakumumpaSchool of Public Health, Makerere University, Kampala, Uganda. zakumumpa@yahoo.com.
Alinaitwe AdolfJoint Clinical Research Centre, Fort Portal Centre of Excellence, Fort Portal, Uganda.
Jepchirchir KiplagatDepartment of Epidemiology and Medical Statistics, School of Public Health, Moi University, Eldoret, Kenya.
Felishana CheropDepartment of Management Science, School of Business and Economics, Moi University, Eldoret, Kenya.
Violet BosireUniversity of the Witwatersrand, School of Public Health, Johannesburg, South Africa.
Esther BuregyeyaSchool of Public Health, Makerere University, Kampala, Uganda.

Funding

Welcome Trust Not applicable
6 · The paper itself

Abstract

introductionAlthough there is an emerging evidence base on the impact of planned donor transitions from HIV programs, there is little research exploring the effects of abrupt cessation of donor aid for HIV programs. We sought to examine the early impacts of PEPFAR funding freeze announced on 20th January 2025 on HIV service delivery in Mid-western Uganda.

methodsWe conducted a qualitative study in the Fort Portal region of mid-Western Uganda, involving 84 participants. In-depth interviews were conducted with 36 health workers in eight purposively selected HIV clinics. Six focus group discussions with a total of 48 participants were conducted with people with HIV (PWH). Data were analyzed by thematic approach.

resultsFour broad themes emerged in our analysis (1) There was uncertainty and confusion across the HIV service delivery landscape right from national-level HIV sector oversight to frontline service delivery. (2) PWH started ‘buffer stocking’ of antiretrovirals which contributed to stock-outs at participating facilities. (3) There was discontinuation of multiple HIV services. The discontinued HIV services include HIV prevention programs, viral load testing, services targeting ‘Key Populations’ and, community outreach for enhancing adherence to HIV/TB treatment including medication distribution through private retail pharmacies which ceased. (4) The loss of PEPFAR-salaried HIV workforce had ripple effects. These include disruptions in routine operations at HIV clinics, sub-national governance mechanisms for HIV services delivery unraveled and loss of PEPFAR-supported community health workers resulted in cessation of community outreach activities while loss of data clerks impeded routine HIV data capture.

conclusionThe abrupt cessation of PEPFAR funding resulted in widespread disruptions to HIV service delivery including discontinuation of multiple HIV services at participating facilities. Our findings highlight the need for planned donor transitions and the need of strengthening the financial, technical, and management capacity of recipient governments for managing previously donor-funded HIV services. Further research on the medium- to long-term impacts of PEPFAR funding freeze is warranted. CLINICAL TRIAL NUMBER: Not applicable.

Indexed as

Delivery of Health CareHIV InfectionsInternational CooperationFemaleFocus GroupsHumansInterviews as TopicQualitative ResearchUgandaDonor transitionHealth systemsHIVInternational assistancePEPFAR

Identifiers

PMID41680802
PMCPMC12997708

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.