Evidence map›Paper›PMID 41680714›Full record

ArticleBMC psychiatry2026

A mixed-method process evaluation of guided online cognitive behavioral therapy for insomnia in patients with borderline personality disorder.

Shanna van Trigt, Femke van Nassau, Tanja van der Zweerde, Eus J W van Someren, Annemieke van Straten, Hein J F van Marle

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Article in BMC psychiatry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

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No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Shanna van TrigtAmsterdam UMC, Location Vrije Universiteit, Psychiatry, De Boelelaan 1117, Amsterdam, the Netherlands. s.vantrigt@amsterdamumc.nl.
Femke van NassauDepartment of Public and Occupational Health, Amsterdam Public Health Research Institute, Amsterdam UMC, Location Vrije Universiteit, Amsterdam, the Netherlands.
Tanja van der ZweerdeVrije Universiteit Amsterdam, Clinical, Neuro and Developmental Psychology, Amsterdam, the Netherlands.
Eus J W van SomerenAmsterdam UMC, Location Vrije Universiteit, Psychiatry, De Boelelaan 1117, Amsterdam, the Netherlands.
Annemieke van StratenAmsterdam Public Health Research Institute, Mental Health Program, Amsterdam, the Netherlands.
Hein J F van MarleAmsterdam UMC, Location Vrije Universiteit, Psychiatry, De Boelelaan 1117, Amsterdam, the Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBorderline personality disorder (BPD) is often associated with insomnia, which may contribute to a vicious cycle of reciprocal exacerbation of sleep disturbance and BPD symptoms. Online cognitive behavioral therapy for insomnia (iCBT-I) has shown promise for treating insomnia in BPD patients. This study evaluated the key determinants, underlying processes, and change mechanisms of successful implementation of guided iCBT-I in BPD patients.

methodsIn the context of our clinical trial, we conducted this mixed-method process evaluation in 30 patients with BPD and comorbid insomnia complaints (mean age 29.5 years ± 8.72) that received guided iCBT-I. Our process evaluation was guided by four dimensions of the theoretical RE-AIM framework: Reach (e.g., reason participation), Effectiveness (e.g., perceived symptom reduction), Implementation (e.g., treatment delivery), Maintenance (e.g., sustained adherence). We combined insights from quantitative patient-reported evaluation of treatment satisfaction and adherence and therapist log data, with qualitative exploration of patient experiences through in-depth interviews in a subsample of five patients.

results21 patients (70%) completed the intervention. Patients appreciated the online modality and emphasized the importance of responsive and personalized (videocall) therapist guidance and active reminders. Patients found behavioral strategies, such as fixed bedtimes and an evening winding-down routine particularly helpful, while more introspective and cognitive techniques were often perceived as challenging. Qualitative effectiveness evaluations aligned with clinical trial outcomes on BPD, insomnia and arousal-related symptoms. Finally, patients expressed a strong desire for more and well-integrated sleep treatment into regular BPD care trajectories.

conclusionsGuided iCBT-I proved a feasible and promising intervention for patients with BPD, with successful implementation contingent upon personalized guidance, focus on behavioral strategies tailored to individual needs, and solid integration into BPD care.

Indexed as

Borderline Personality DisorderCognitive Behavioral TherapySleep Initiation and Maintenance DisordersAdultFemaleHumansMaleMental Health TeletherapyPatient SatisfactionTreatment OutcomeYoung AdultBorderline personality disorderCognitive behavioral therapy for insomniaImplementationInsomniaProcess evaluationSleep

Identifiers

PMID41680714
PMCPMC12997894

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.