Evidence map›Paper›PMID 41680631›Full record

ArticleBMC genomics2026

Deciphering the genetic determinants of calcium, iron, magnesium and zinc accumulation in grain amaranth (Amaranthus hypochondriacus) through a multi environment GWAS approach.

Sharat Prabhakaran, Rashmi Chauhan, Dinesh Chandra Joshi, Sundip Kumar, Jajati Keshari Nayak, Rahul Chandora, J P Jaiswal, Dinesh Pandey

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC genomics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Sharat PrabhakaranDepartment of Molecular Biology & Genetic Engineering, College of Basic Sciences & Humanities, G.B. Pant University of Agriculture and Technology, Pantnagar, Uttarakhand, India.
Rashmi ChauhanDepartment of Molecular Biology & Genetic Engineering, College of Basic Sciences & Humanities, G.B. Pant University of Agriculture and Technology, Pantnagar, Uttarakhand, India.
Dinesh Chandra JoshiDivision of Crop Improvement, ICAR-Vivekananda Institute of Hill Agriculture (Vivekananda Parvatiya Krishi Anusandhan Sansthan), Almora, Uttarakhand, India. dinesh.pbl@gmail.com.ORCID http://orcid.org/0000-0002-4841-7281
Sundip KumarDepartment of Molecular Biology & Genetic Engineering, College of Basic Sciences & Humanities, G.B. Pant University of Agriculture and Technology, Pantnagar, Uttarakhand, India.
Jajati Keshari NayakDepartment of Molecular Biology & Genetic Engineering, College of Basic Sciences & Humanities, G.B. Pant University of Agriculture and Technology, Pantnagar, Uttarakhand, India.
Rahul ChandoraICAR-NBPGR (Regional Station), Shimla, Himachal Pradesh, India.
J P JaiswalDepartment of Genetics & Plant Breeding, College of Agriculture, G.B. Pant University of Agriculture and Technology, Pantnagar, Uttarakhand, India.
Dinesh PandeyDepartment of Molecular Biology & Genetic Engineering, College of Basic Sciences & Humanities, G.B. Pant University of Agriculture and Technology, Pantnagar, Uttarakhand, India. dineshpandey.bmb@gbpuat.ac.in.ORCID http://orcid.org/0000-0002-9569-4580

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Micronutrient malnutrition poses a global challenge, highlighting the need for biofortified crops with enhanced mineral density. Grain amaranth (Amaranthus hypochondriacus), a nutrient-rich pseudocereal, offers high levels of essential minerals, yet its genetic basis for mineral accumulation remains poorly understood. We evaluated 192 diverse accessions across two contrasting environments for calcium (Ca), iron (Fe), magnesium (Mg), and zinc (Zn) content, which varied from 90.5 to 249.7 mg/100 g (1.8-fold) for Ca, 6.8-35.7 mg/100 g (5.2-fold) for Fe, 182.2-471.7 mg/100 g (2.6-fold) for Mg, and 2.6-9.2 mg/100 g (3.6-fold) for Zn. High broad-sense heritability (H² ≥ 0.87) and substantial genetic advance confirmed strong genetic control and scope for selection. A multi-locus genome-wide association study using 41,931 SNPs identified 368 significant associations, of which 25 environmentally stable marker trait associations (MTAs) were detected across traits. Candidate gene analysis revealed 92 putative genes related to mineral homeostasis, and expression profiling validated functional relevance of key candidates. This study provides a comprehensive genomic framework for marker-assisted breeding of biofortified amaranth cultivars with enhanced mineral density.

Indexed as

AmaranthusCalciumGenome-Wide Association StudyIronMagnesiumZincPhenotypePolymorphism, Single NucleotideQuantitative Trait LociCalciumIronMagnesiumZincAmaranthCandidate genesGene expressionGrain mineral contentGWASMarker trait associationPseudocereal

Identifiers

PMID41680631
PMCPMC13005450

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.