Evidence map›Paper›PMID 41680491›Full record

ArticleInternational journal of obesity (2005)2026

Adherence to positive airway pressure therapy and healthcare resource utilization and costs among patients with obstructive sleep apnea and obesity.

Fatima H Sert Kuniyoshi, Ann Cameron, Jean-Louis Pépin, R Benjamin Dexter, Caleb Woodford, Peter A Cistulli, Naomi Alpert, Kimberly L Sterling, Atul Malhotra, medXcloud group

Abstract read
In one paragraph

Article in International journal of obesity (2005), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Fatima H Sert Kuniyoshi *Resmed Science Center, San Diego, CA, USA. fatima.sert@resmed.com.ORCID http://orcid.org/0000-0001-7644-7384
Ann Cameron *Resmed Science Center, San Diego, CA, USA.
Jean-Louis PépinGrenoble Alpes University, Inserm U1300, CHU Grenoble Alpes, HP2, Grenoble, France.
R Benjamin DexterResmed Science Centre, Halifax, NS, Canada.ORCID http://orcid.org/0009-0005-1943-9181
Caleb WoodfordResmed Science Centre, Halifax, NS, Canada.ORCID http://orcid.org/0000-0003-1107-8607
Peter A CistulliDepartment of Respiratory and Sleep Medicine, Royal North Shore Hospital, Charles Perkins Centre, Faculty of Medicine and Health, University of Sydney, Sydney, NSW, Australia.ORCID http://orcid.org/0000-0002-7920-4924
Naomi AlpertResmed Science Center, San Diego, CA, USA.ORCID http://orcid.org/0000-0002-3625-9693
Kimberly L SterlingResmed Science Center, San Diego, CA, USA.
Atul MalhotraUniversity of California San Diego, La Jolla, CA, USA.
medXcloud group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveObstructive sleep apnea (OSA) and obesity are highly prevalent comorbid conditions associated with major societal and healthcare burden. Positive airway pressure (PAP) therapy is the first-line treatment for OSA. This study evaluated the association between PAP adherence and healthcare resource utilization (HCRU) and costs in patients with OSA and comorbid obesity.

methodsThis retrospective cohort study utilized de-identified claims data linked with cloud-connected PAP usage to analyze adults with obesity (ICD-10 code of obesity or morbid obesity or indicating BMI ≥ 30 kg/m

resultsAmong 173,691 patients, 35.2% were adherent, 39.1% intermediately adherent, and 25.7% nonadherent. After applying inverse probability of treatment weighting (IPTW), in year 1 post-index, adherent patients had significantly fewer ER visits and hospitalizations (0.55 ± 1.77 and 0.10 ± 0.44) compared to nonadherent patients (0.69 ± 1.78 and 0.14 ± 0.56; P < 0.001), and significantly lower total healthcare costs (11,332 ± 21,160 vs 11,927 ± 20,212; P < 0.001). Similar findings were observed after 2 years of therapy with adherent patients having lower HCRU and costs than nonadherent patients. Patients with intermediate adherence had outcomes between those of adherent and nonadherent groups, suggesting a dose-dependent effect.

conclusionsGreater adherence to PAP therapy is associated with significantly lower HCRU and costs in patients with OSA and obesity, highlighting the importance of implementing strategies to improve long term PAP adherence, potentially reducing economic and clinical burden.

Indexed as

Continuous Positive Airway PressureHealth Care CostsObesityPatient Acceptance of Health CarePatient ComplianceSleep Apnea, ObstructiveAdultAgedFemaleHumansMaleMiddle AgedRetrospective Studies

Identifiers

PMID41680491
PMCPMC13056527

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.