Evidence map›Paper›PMID 41680305›Full record

ArticleFunctional & integrative genomics2026

Genome-wide identification of the BXL gene family in potato (Solanum tuberosum) and functional characterization of StBXL4 in disease resistance.

Yuxin Li, Yuhan Zhang, Ying Shi, Xia Zhu, Jingye Fu, Qiang Wang

Abstract read
PubMed Publisher
In one paragraph

Article in Functional & integrative genomics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yuxin LiState Key Laboratory of Crop Gene Exploration and Utilization in Southwest China, College of Agronomy, Sichuan Agricultural University, Chengdu, 611130, China.
Yuhan ZhangState Key Laboratory of Crop Gene Exploration and Utilization in Southwest China, College of Agronomy, Sichuan Agricultural University, Chengdu, 611130, China.
Ying ShiState Key Laboratory of Crop Gene Exploration and Utilization in Southwest China, College of Agronomy, Sichuan Agricultural University, Chengdu, 611130, China.
Xia ZhuShannan Agricultural Technology Promotion Center, Shannan, 856099, China.
Jingye FuState Key Laboratory of Crop Gene Exploration and Utilization in Southwest China, College of Agronomy, Sichuan Agricultural University, Chengdu, 611130, China. Jingyefu@sicau.edu.cn.
Qiang WangState Key Laboratory of Crop Gene Exploration and Utilization in Southwest China, College of Agronomy, Sichuan Agricultural University, Chengdu, 611130, China. qwang@sicau.edu.cn.

Funding

Open Project Program of Panxi Crop Improvement Key Laboratory of Sichuan Province SZKF210Open Project Program of Panxi Crop Improvement Key Laboratory of Sichuan Province SZKF2204Shannan Science and Technology Project SNSBJKJJHXM2024001Sichuan Potato Innovation Team Project of the Chinese Modern Agricultural Industrial Technology System SCCXTD-2025-09
6 · The paper itself

Abstract

The β-D-xylosidase (BXL) gene family, belonging to the glycoside hydrolase GH3 family, plays a crucial role in cell wall remodeling and plant defense. However, its genomic characterization and functional roles in potato (Solanum tuberosum) remain unexplored. In this study, seven StBXL genes (StBXL1–StBXL7) were systematically identified from the potato genome, all harboring conserved Glyco_hydro_3 and Glyco_hydro_3_C domains, indicating evolutionary conservation comparable to Arabidopsis. Promoter analysis revealed enrichment of hormone-responsive (e.g., MeJA-related CGTCA/TGACG motifs), abiotic stress-related, and growth-regulatory cis-elements, suggesting integration of hormonal and environmental signals in defense regulation. Expression profiling demonstrated that Phytophthora infestans infection significantly induced StBXL4 expression. Functional assays in Nicotiana benthamiana showed that StBXL4 overexpression enhanced resistance to P. infestans by upregulating salicylic acid (SA)- and jasmonic acid (JA)-responsive genes (NbPR1A, NbPR2, NbPR5, NbICS1, NbMYC2), pattern-triggered immunity (PTI) marker genes (WRKY7, WRKY8), and antioxidant enzymes (POD), thereby reducing excessive H₂O₂ accumulation. Conversely, silencing of NbBXL4 increased disease susceptibility and impaired ROS scavenging capacity. These findings reveal that StBXL4 acts as a dual-function regulator in potato immunity by maintaining ROS homeostasis and coordinating multiple defense signaling pathways. This study not only fills the genomic gap of the potato BXL family but also identifies StBXL4 as a promising candidate for molecular breeding strategies to enhance durable late blight resistance.

Indexed as

Disease ResistancePlant DiseasesPlant ProteinsSolanum tuberosumCyclopentanesGene Expression Regulation, PlantMultigene FamilyOxylipinsPhytophthora infestansSalicylic AcidCyclopentanesjasmonic acidOxylipinsPlant ProteinsSalicylic AcidBXL gene familyLate blight resistanceROS homeostasisSA/JA signalingSolanum tuberosumStBXL4

Identifiers

PMID41680305

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.