Evidence map›Paper›PMID 41680231›Full record

ArticleScientific data2026

A time-series transcriptomic dataset of the mouse olfactory bulb across pregnancy and lactation.

Xiaolei Song, Gengwei Zhang, Fengzhu Zhang, Tongye Fu, Jingzhe Yu, Danyu Han, Wenhui Li, Rongliang Guo

Abstract readDataset
In one paragraph

Article in Scientific data, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Xiaolei Song *Collaborative Innovation Center for Biomedicine, Shanghai University of Medicine and Health Sciences, Shanghai, China. songxl@sumhs.edu.cn.
Gengwei Zhang *School of Clinical Medicine, Hebei University of Engineering, Handan, Hebei, China.
Fengzhu ZhangShanghai Yangpu District Mental Health Center, Shanghai University of Medicine and Health Sciences, Shanghai, China.
Tongye FuState Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Institutes of Brain Science, Fudan University, Shanghai, China.
Jingzhe YuState Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Institutes of Brain Science, Fudan University, Shanghai, China.
Danyu HanState Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Institutes of Brain Science, Fudan University, Shanghai, China.
Wenhui LiCollaborative Innovation Center for Biomedicine, Shanghai University of Medicine and Health Sciences, Shanghai, China.
Rongliang GuoSchool of Clinical Medicine, Hebei University of Engineering, Handan, Hebei, China. rlguo20@fudan.edu.cn.

Funding

Health Commission of Hebei Province 20250165National Natural Science Foundation of China 82501435Natural Science Foundation of Hebei Province H2025402018
6 · The paper itself

Abstract

Olfaction is the primary sensory modality governing maternal behavior in rodents. To meet the demands of maternal care, the brain undergoes extensive and temporally dynamic plasticity during the perinatal period, particularly within the olfactory bulb (OB). However, longitudinal data describing the molecular landscape of the OB across the entire reproductive cycle are currently unavailable. We generated a high-resolution transcriptomic dataset of the mouse OB to map molecular reprogramming events during reproduction. Samples were collected at five strategic time points: non-pregnancy, gestation day 10, parturition, postpartum day 7, and weaning. Using bulk RNA-seq, we constructed a dynamic transcriptomic atlas of the maternal OB. This dataset captures stage-specific gene expression changes associated with neurogenesis, synaptic plasticity, and neuromodulation. This work provides a critical molecular resource to facilitate future research into the adaptive remodeling of the maternal neural circuit.

Indexed as

LactationOlfactory BulbTranscriptomeAnimalsFemaleMiceNeurogenesisNeuronal PlasticityPregnancy

Identifiers

PMID41680231
PMCPMC13009226

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.