ArticleMicrosystems & nanoengineering2026
Vertical graphene-coated core-shell microneedle as miniatured sensor for in vivo glucose monitoring.
Article in Microsystems & nanoengineering, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Microneedle-based continuous glucose monitoring systems have advanced diabetes management in pain less manner, but challenges remain regarding detection sensitivity due to limited sensing area. Vertical graphene (VG) with large surface area offers high conductivity and excellent electrochemical properties for miniaturized, high-performance biomedical sensors. In this study, we developed a vertical graphene-coated core-shell microneedle glucose sensor (VCMGS) for continuous monitoring of glucose fluctuations. The VCMGS featured a hollow microneedle as the outer shell for effective skin penetration, coupled with a vertical graphene-modified sensing electrode core for glucose detection subcutaneously. The core-shell structure provides robust mechanical strength, minimizing damage to the sensing area and improving overall sensor stability. Meanwhile, the electrochemical performance and sensitivity of the microneedle electrode was enhanced by VG, enabling reliable, in situ, and real-time physiological signal acquisition from interstitial fluid. The VCMGS exhibited sensitive response to glucose variations, with a well-defined linear relationship, high selectivity, temporal stability, and dependable signal transmission in both in vitro and in vivo experiments, demonstrating high capability for precise, continuous tracking of glucose fluctuations in real time. This work offered potential applicability and benefits in aiding the diagnosis and treatment of diabetes.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.