Evidence map›Paper›PMID 41678311›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2026

High-speed atomic force microscopy reveals a surface-catalyzed elongation mechanism of the fungal functional amyloid hydrophobin RolA.

Nao Takahashi, Tatsuya Kimura, Yuki Terauchi, Takumi Tanaka, Natsuki Abe, Akira Yoshimi, Takahiro Watanabe-Nakayama, Keietsu Abe

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Nao TakahashiMajor of Agricultural Chemistry, Graduate School of Agricultural Science, Tohoku University, Sendai, Miyagi 980-8572, Japan.ORCID 0009-0002-5547-4089
Tatsuya KimuraWorld Premier International Research Center Initiative Nano Life Science Institute, Kanazawa University, Kanazawa, Ishikawa 920-1192, Japan.
Yuki TerauchiResearch Center for Thermotolerant Microbial Resources, Yamaguchi University, Yamaguchi, Yamaguchi 753-8511, Japan.
Takumi TanakaMajor of Agricultural Chemistry, Graduate School of Agricultural Science, Tohoku University, Sendai, Miyagi 980-8572, Japan.
Natsuki AbeMajor of Agricultural Chemistry, Graduate School of Agricultural Science, Tohoku University, Sendai, Miyagi 980-8572, Japan.
Akira YoshimiDivision of Environmental Science and Technology, Graduate School of Agriculture, Kyoto University, Kyoto 606-8502, Japan.
Takahiro Watanabe-NakayamaWorld Premier International Research Center Initiative Nano Life Science Institute, Kanazawa University, Kanazawa, Ishikawa 920-1192, Japan.
Keietsu AbeMajor of Agricultural Chemistry, Graduate School of Agricultural Science, Tohoku University, Sendai, Miyagi 980-8572, Japan.ORCID 0000-0001-5344-3794

Funding

MEXT | Japan Society for the Promotion of Science (JSPS) 23K26810 (K.A.)MEXT | Japan Society for the Promotion of Science (JSPS) 24KJ0419 (N.T.)Noda Institute for Scientific Research (NISR) (K.A.)WPI-Nano Life Science Institute and World Premier International Research Center Initiative Bio-SPM Collaborative Research (K.A.)
6 · The paper itself

Abstract

Hydrophobins are functional amyloids conserved in filamentous fungi. They act as a protective coat in the fibrous form, called rodlet. Rodlets further assemble to form dense films where they are bundled and densely aligned, contributing to the hydrophobicity of the mycelium surface. The mechanism of this dense film formation is completely unknown. Here, we used high-speed atomic force microscopy to directly observe the structural dynamics of rodlet bundling and subsequent film formation by hydrophobin RolA from the industrial fungus

Indexed as

AmyloidAspergillus oryzaeFungal ProteinsMicroscopy, Atomic ForceHydrophobic and Hydrophilic InteractionsSurface PropertiesAmyloidFungal Proteinsfilamentous fungifunctional amyloidhigh-speed AFMhydrophobinsurface-catalyzed elongation

Identifiers

PMID41678311
PMCPMC12912973

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.