Evidence map›Paper›PMID 41678027›Full record

ArticleBulletin of mathematical biology2026

A mathematical model to simulate the biological action of Infliximab on TNF-

Ana M Portillo, Ángel De Prado, Ana J Soares

Abstract read
In one paragraph

Article in Bulletin of mathematical biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Ana M PortilloInstituto de Investigación en Matemáticas, University of Valladolid, Paseo Belén, 47011, Valladolid, Spain. ana.portillo@uva.es.ORCID https://orcid.org/0000-0003-3686-5033
Ángel De PradoMucosal Immunology Laboratory, Instituto de Biomedicina y Genética Molecular (IBGM), University of Valladolid-CSIC, Calle Sanz y Forés, 3, 47003, Valladolid, Spain.ORCID https://orcid.org/0000-0002-0327-9153
Ana J SoaresCentre of Mathematics, University of Minho, Campus of Gualtar, 4710-057, Braga, Portugal.ORCID https://orcid.org/0000-0003-4771-9859

Funding

Centro de Matemática, Universidade do Minho UID/00013FCT/MCTES CoSysM32022.03091.PTDCMinisterio de Ciencia, Innovación y Universidades PID2023-147073NB-I00
6 · The paper itself

Abstract

Inflammatory bowel disease (IBD), including Crohn s disease (CD) and ulcerative colitis (UC), is characterized by chronic intestinal inflammation driven by elevated tumor necrosis factor-alpha (TNF-

Indexed as

Gastrointestinal AgentsInflammatory Bowel DiseasesInfliximabModels, BiologicalTumor Necrosis Factor-alphaColitis, UlcerativeComputer SimulationCrohn DiseaseHumansMathematical ConceptsTreatment OutcomeGastrointestinal AgentsInfliximabTumor Necrosis Factor-alphaBiologic therapyDrug clearanceInflammatory bowel diseaseInfliximabMathematical modellingTNF-

Identifiers

PMID41678027
PMCPMC12901222

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.