ArticleArchives of orthopaedic and trauma surgery2026
Effect of prior mastectomy on outcomes following total shoulder arthroplasty.
Article in Archives of orthopaedic and trauma surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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8 authors.
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Abstract
backgroundMastectomy and its associated treatments may alter shoulder biomechanics and soft-tissue integrity, yet their impact on total shoulder arthroplasty (TSA) outcomes remains unclear. This study evaluated short- and long-term complications following TSA in patients with a history of mastectomy.
methodsA retrospective cohort analysis was performed using the TriNetX Research Network, including patients who underwent primary TSA. Individuals with a history of mastectomy were identified using procedural and diagnostic coding, and those with contralateral mastectomy and TSA were excluded. Propensity score matching 1:1 was performed to balance demographics and comorbidities. Ninety-day and two-year outcomes were compared between matched cohorts.
resultsAfter matching, 1,865 patients with prior mastectomy were compared with 1,865 controls. Patients with a history of mastectomy had a significantly higher incidence of postoperative lymphedema (3.48% vs. 0.67%; RR 5.15; P < .0001). They also demonstrated increased risk of venous thromboembolism (4.56% vs. 3.11%; RR 1.47; P = .018). Overall postoperative infection rates were higher in the mastectomy cohort (3.96% vs. 2.70%; RR 1.47; P = .0378), including higher rates of cellulitis (2.81% vs. 1.72%; RR 1.63; P = .031). No significant differences were observed for 2-year outcomes.
conclusionPatients with a history of mastectomy undergoing TSA are at increased risk of perioperative postoperative lymphedema, thromboembolic events, and cellulitis. These findings highlight the importance of heightened perioperative surveillance.
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