Evidence map›Paper›PMID 41677654›Full record

ArticleCells2026

CD74-Targeted Cathepsin-Inhibitor Antibody-Drug Conjugate Triggers Apoptosis in DLBCL.

Ihab Abd-Elrahman, Noha Khairi, Reut Sinai-Turyansky, Ivan Zlotber, Riki Perlman, Emmanuelle Merquiol, Galia Blum, Dina Ben Yehuda

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cells, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ihab Abd-ElrahmanDepartment of Hematology, Hadassah Medical Center, Jerusalem 9112001, Israel.ORCID 0000-0003-2012-2024
Noha KhairiDepartment of Hematology, Hadassah Medical Center, Jerusalem 9112001, Israel.
Reut Sinai-TuryanskyFaculty of Medicine, The Hebrew University of Jerusalem, Jerusalem 9112001, Israel.
Ivan ZlotberFaculty of Medicine, The Hebrew University of Jerusalem, Jerusalem 9112001, Israel.
Riki PerlmanDepartment of Hematology, Hadassah Medical Center, Jerusalem 9112001, Israel.
Emmanuelle MerquiolFaculty of Medicine, The Hebrew University of Jerusalem, Jerusalem 9112001, Israel.
Galia BlumFaculty of Medicine, The Hebrew University of Jerusalem, Jerusalem 9112001, Israel.
Dina Ben YehudaDepartment of Hematology, Hadassah Medical Center, Jerusalem 9112001, Israel.

Funding

Israel Science Foundation 1638/19Israel Science Foundation 2704/19
6 · The paper itself

Abstract

Transcriptomic analyses of public datasets (TCGA and GTEx) revealed that both

Indexed as

Antigens, Differentiation, B-LymphocyteApoptosisCathepsin LCathepsinsImmunoconjugatesLymphoma, Large B-Cell, DiffuseCell Line, TumorHistocompatibility Antigens Class IIHumansAntigens, Differentiation, B-LymphocyteCathepsin LCathepsinsHistocompatibility Antigens Class IIImmunoconjugatesinvariant chainantibody–drug conjugates (ADC)cathepsinscell deathdiffuse large B-cell lymphoma

Identifiers

PMID41677654
PMCPMC12896589

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.