Evidence map›Paper›PMID 41677626›Full record

ArticleCells2026

Adipose Tissue-Derived Exosome and miR-142a-3p Alleviate Acute Lung Injury by Inhibiting HMGB1-Driven Autophagy.

Qianlin Long, Kejie Chen, Yizhu Li, Ruinan Peng, Yijian Yan, Jintao Ma, Jia Wang, Qiuyu Song, Yu Xue, Fengyuan Wang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cells, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Qianlin LongCollege of Animal & Veterinary Sciences, Southwest Minzu University, Chengdu 610041, China.
Kejie ChenSchool of Public Health, Chengdu Medical College, Chengdu 610500, China.
Yizhu LiCollege of Animal & Veterinary Sciences, Southwest Minzu University, Chengdu 610041, China.
Ruinan PengCollege of Animal & Veterinary Sciences, Southwest Minzu University, Chengdu 610041, China.
Yijian YanCollege of Animal & Veterinary Sciences, Southwest Minzu University, Chengdu 610041, China.
Jintao MaSchool of Public Health, Chengdu Medical College, Chengdu 610500, China.
Jia WangSchool of Public Health, Chengdu Medical College, Chengdu 610500, China.
Qiuyu SongSchool of Public Health, Chengdu Medical College, Chengdu 610500, China.
Yu XueSchool of Public Health, Chengdu Medical College, Chengdu 610500, China.
Fengyuan WangCollege of Animal & Veterinary Sciences, Southwest Minzu University, Chengdu 610041, China.

Funding

Fundamental Research Funds for the Central Universities, Southwest Minzu University ZYN2023049Sichuan Provincial Administration of Traditional Chinese Medicine 2024MS517
6 · The paper itself

Abstract

Acute lung injury (ALI) is a clinically severe respiratory disorder, of which autophagy is the crucial mechanism. Exosomes have the potential to treat ALI, but the role of adipose-derived exosomes (ADEs) in the autophagy of ALI remains unclear. Using an LPS-induced ALI model, the effects of ADE isolated from a lean or diet-induced-obese (DIO) mouse and ADE-carried miRNAs were investigated. After administration of ADEs, the levels of autophagy-related molecules were determined by qRT-PCR, Western blotting, and immunohistochemical staining. Then, a miRNA targeting

Indexed as

Acute Lung InjuryAdipose TissueAutophagyExosomesHMGB1 ProteinMicroRNAsAnimalsHumansLipopolysaccharidesMaleMiceMice, Inbred C57BLHMGB1 ProteinHMGB1 protein, mouseLipopolysaccharidesMicroRNAsMirn142 microRNA, mouseacute lung injuryautophagyexosomemiR-142a-3p

Identifiers

PMID41677626
PMCPMC12897417

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.