Evidence map›Paper›PMID 41677610›Full record

ArticleCells2026

Effects of Bovine Milk-Derived Extracellular Vesicles on a 3D Intestinal Stromal Compartment.

Georgia Pennarossa, Sharon Arcuri, Madhusha Prasadani, Fulvio Gandolfi, Alireza Fazeli, Tiziana A L Brevini

Abstract read
In one paragraph

Article in Cells, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Decellularized testicular bio-scaffolds driveFrontiers in bioengineering and biotechnology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Georgia PennarossaLaboratory of Biomedical Embryology and Tissue Engineering, Department of Veterinary Medicine and Animal Sciences, Centre for Stem Cell Research, Università degli Studi di Milano, 26900 Lodi, Italy.ORCID 0000-0001-6126-8519
Sharon ArcuriLaboratory of Biomedical Embryology and Tissue Engineering, Department of Veterinary Medicine and Animal Sciences, Centre for Stem Cell Research, Università degli Studi di Milano, 26900 Lodi, Italy.
Madhusha PrasadaniInstitute of Veterinary Medicine and Animal Sciences, Estonian University of Life Sciences, 50303 Tartu, Estonia.ORCID 0000-0001-8961-8875
Fulvio GandolfiDepartment of Agricultural and Environmental Sciences-Production, Landscape, Agroenergy, Università degli Studi di Milano, 20134 Milan, Italy.ORCID 0000-0002-3246-2985
Alireza FazeliInstitute of Veterinary Medicine and Animal Sciences, Estonian University of Life Sciences, 50303 Tartu, Estonia.ORCID 0000-0003-0870-9914
Tiziana A L BreviniLaboratory of Biomedical Embryology and Tissue Engineering, Department of Veterinary Medicine and Animal Sciences, Centre for Stem Cell Research, Università degli Studi di Milano, 26900 Lodi, Italy.ORCID 0000-0002-0428-3621

Funding

HORIZON-WIDERA-2021 101079349
6 · The paper itself

Abstract

Milk is an essential component of the diet. Among its diverse molecular constituents, it contains nanoscale entities, known as extracellular vesicles (EVs), which play a pivotal role in intercellular communication. In particular, milk-derived EVs (MEVs) influence intestinal homeostasis by mitigating inflammatory responses, modulating gut microbiota composition, and contributing to epithelial integrity preservation and restoration. Currently, there are no information regarding their impact on intestinal connective tissue. Here, we investigate bovine MEV effects on the porcine gut stromal compartment, exposing intestinal decellularized bio-scaffolds repopulated with primary intestinal stromal fibroblasts, to different MEV concentrations (10

Indexed as

Extracellular VesiclesIntestinesMilkStromal CellsAnimalsCattleCell ProliferationFibroblastsIntestinal MucosaSwineTissue Scaffolds3D stromal compartmentbovine milk-derived extracellular vesiclesdecellularizationintestinal bio-scaffolds

Identifiers

PMID41677610
PMCPMC12896473

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.