Evidence map›Paper›PMID 41677591›Full record

ArticleCells2026

Lactic Acid Bacteria Postbiotics as Adjunctives to Glioblastoma Therapy to Fight Treatment Escape and Protect Non-Neoplastic Cells from Side Effects.

Pola Głowacka, Agnieszka Pudlarz, Joanna Wasiak, Magdalena Peszyńska-Piorun, Michał Biegała, Karol Wiśniewski, Dariusz J Jaskólski, Adam Marek Pieczonka, Tomasz Płoszaj, Janusz Szemraj and 1 more

Abstract read
In one paragraph

Article in Cells, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Pola GłowackaDepartment of Medical Biochemistry, Medical University of Lodz, 6/8 Mazowiecka Str., 92-215 Lodz, Poland.ORCID 0000-0001-7996-5101
Agnieszka PudlarzDepartment of Medical Biochemistry, Medical University of Lodz, 6/8 Mazowiecka Str., 92-215 Lodz, Poland.ORCID 0000-0001-5935-7432
Joanna WasiakDepartment of Medical Biochemistry, Medical University of Lodz, 6/8 Mazowiecka Str., 92-215 Lodz, Poland.
Magdalena Peszyńska-PiorunRadiotherapy Planning Department, Copernicus Memorial Hospital in Lodz Comprehensive Cancer Center and Traumatology, 93-513 Lodz, Poland.
Michał BiegałaDepartment of Medical Imaging Technology, Faculty of Medicine, Medical University of Lodz, Narutowicza 60, 90-136 Lodz, Poland.ORCID 0000-0002-0283-5912
Karol WiśniewskiDepartment of Neurosurgery and Neuro-Oncology, Medical University of Lodz, Barlicki University Hospital, Kopcinskiego St. 22, 90-153 Lodz, Poland.
Dariusz J JaskólskiDepartment of Neurosurgery and Neuro-Oncology, Medical University of Lodz, Barlicki University Hospital, Kopcinskiego St. 22, 90-153 Lodz, Poland.ORCID 0000-0002-9971-9677
Adam Marek PieczonkaDepartment of Organic and Applied Chemistry, Faculty of Chemistry, University of Lodz, Tamka 12, 91-403 Lodz, Poland.ORCID 0000-0001-6526-315X
Tomasz PłoszajDepartment of Clinical Genetics, Medical University of Lodz, Pomorska Str. 251, 92-213 Lodz, Poland.ORCID 0000-0002-9503-278X
Janusz SzemrajDepartment of Medical Biochemistry, Medical University of Lodz, 6/8 Mazowiecka Str., 92-215 Lodz, Poland.ORCID 0000-0001-6052-3557
Monika Witusik-PerkowskaDepartment of Medical Biochemistry, Medical University of Lodz, 6/8 Mazowiecka Str., 92-215 Lodz, Poland.ORCID 0000-0002-8556-2859

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite tremendous scientific efforts aimed at glioblastoma's (GB) ability to escape therapeutic attempts, the concern remains unsolved. Postbiotics, metabolites, and macromolecules of probiotic bacteria could become adjuvant therapeutics both dealing with cellular events constituting tumor therapy escape mechanisms and protecting normal cells from therapy-induced damage. The study aims to evaluate the dual potential of postbiotics obtained from lactic acid bacteria,

Indexed as

Brain NeoplasmsGlioblastomaLactobacillalesProbioticsApoptosisCell Line, TumorHumanschemotherapyglioblastomalactic acid bacteriapostbioticsradiotherapysenescence

Identifiers

PMID41677591
PMCPMC12897306

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.