ArticleVeterinary medicine and science2026
Effect of Bifidobacterium Probiotic Supplementation on Interleukin-6 Levels and Osteoclast Count in Wistar Rats During Orthodontic Tooth Movement.
Article in Veterinary medicine and science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Effect of Bifidobacterium Probiotic Supplementation on Interleukin-6 Levels and Osteoclast Count in Wistar Rats During Orthodontic Tooth Movement.Veterinary medicine and science · 2026Article
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4 authors.
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Abstract
backgroundProbiotics may offer benefits in mitigating bone loss and related conditions. Bone resorption is essential for bone remodelling, particularly during orthodontic tooth movement induced by mechanical forces. This study investigates the effects of Bifidobacterium probiotic supplementation on interleukin-6 (IL-6) levels and osteoclast counts. METHODS AND MATERIALS: This study involved 48 healthy male Wistar rats, randomly assigned to six groups: control groups at 3 days (C3), 7 days (C7) and 14 days (C14), and probiotic groups at 3 days (P3), 7 days (P7) and 14 days (P14). The probiotic group received a daily gavage of Bifidobacterium at a dose of 1.5 × 10
resultsProbiotic supplementation resulted in a significant reduction in IL-6 levels and osteoclast counts compared to the control group. Peak IL-6 levels and osteoclast counts in the control group were observed on Day 14, whereas the lowest levels were recorded in the probiotic group on the same day.
conclusionDespite certain limitations, this study suggests that Bifidobacterium animalis subsp. lactis supplementation effectively reduces IL-6 levels and osteoclast counts during orthodontic tooth movement over a 14-day period when compared to controls.
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