Evidence map›Paper›PMID 41676985›Full record

ArticleDiseases of the colon and rectum2026

"Nobody Told Me": A Qualitative Study of Sexual and Reproductive Concerns After Treatment for Early-Onset Colorectal Cancer.

Samantha L Savitch, Sarah E Bradley, C Ann Vitous, Maedeh Marzoughi, Claire C Ashmead-Meers, Clare E Jacobson, Tabitha E Norton, Jordan L Boyce-Suwanabol, Pasithorn A Suwanabol

Abstract read
In one paragraph

Article in Diseases of the colon and rectum, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Samantha L SavitchDepartment of Surgery, University of Michigan Health System, Ann Arbor, Michigan.
Sarah E BradleyCenter for Healthcare Outcomes and Policy, University of Michigan, Ann Arbor, Michigan.
C Ann VitousCenter for Healthcare Outcomes and Policy, University of Michigan, Ann Arbor, Michigan.
Maedeh MarzoughiUniversity of Michigan Medical School, Ann Arbor, Michigan.
Claire C Ashmead-MeersDepartment of Internal Medicine, Mayo Clinic, Rochester, Minnesota.
Clare E JacobsonDepartment of Surgery, University of Michigan Health System, Ann Arbor, Michigan.
Tabitha E NortonHoward University College of Medicine, Washington, District of Columbia.
Jordan L Boyce-SuwanabolCenter for Healthcare Outcomes and Policy, University of Michigan, Ann Arbor, Michigan.
Pasithorn A SuwanabolDepartment of Surgery, University of Michigan Health System, Ann Arbor, Michigan.

Funding

Interdisciplinary Research Training Center in Cancer Care DeliveryT32CA236621 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Lauren P Wallner · 2020 to 2026
$2.8M
NCI NIH HHS T32 CA236621
6 · The paper itself

Abstract

backgroundThe incidence of early-onset colorectal cancer is rising, yet survivorship care guidelines rarely address concerns unique to younger adults. Although treatment for colorectal cancer can have devastating consequences related to sexual function and fertility, these issues remain underrecognized and seldom addressed.

objectiveTo better understand the impact of colorectal cancer diagnosis and treatment on sexual and reproductive health.

designQualitative study of patients with early-onset colorectal cancer. SETTINGS: Semi-structured one-to-one Zoom interviews of patients recruited through convenience sampling from 7 academic institutions. PATIENTS: Sixty-three individuals diagnosed with colorectal cancer aged 50 years or younger were interviewed between March 2021 and August 2024.

main outcome measuresPatient perspectives regarding the sexual and reproductive health impacts of colorectal cancer diagnosis and treatment. Data were analyzed iteratively using directed and conventional qualitative content analysis.

resultsParticipants discussed sexual and reproductive health side effects resulting from surgery, chemotherapy, and radiation. These side effects ranged in severity, with some experiencing almost none and others facing significant issues. They identified several domains, including surgical and treatment side effects, psychological impacts, effects on relationships, and unmet needs. Subdomains included sexual health, reproductive health, emotional distress, body image, communication challenges, impacts on dating, informational needs, financial support, and consultations. LIMITATIONS: Participants were recruited from academic medical centers only, and as such, responses may not reflect the experiences of those cared for in nonacademic settings.

conclusionsSexual and reproductive health are critical but often overlooked concerns among younger patients with CRC, with significant impacts on physical functioning, partner relationships, and psychological well-being. Current survivorship guidelines fail to adequately address these needs. Our findings highlight the importance of pretreatment counseling and fertility preservation as well as the need for ongoing mental health support during and after cancer treatment. See Video Abstract . NADIE ME LO DIJO ESTUDIO CUALITATIVO SOBRE LAS PREOCUPACIONES SEXUALES Y REPRODUCTIVAS TRAS EL TRATAMIENTO DEL CNCER COLORRECTAL DE APARICIN TEMPRANA: ANTECEDENTES:La incidencia del cáncer colorrectal de aparición temprana está aumentando, pero las directrices sobre cuidados para supervivientes rara vez abordan las preocupaciones específicas de los adultos jóvenes. Aunque el tratamiento del cáncer colorrectal puede tener consecuencias devastadoras para la función sexual y la fertilidad, estas cuestiones siguen sin reconocerse lo suficiente y rara vez se abordan.OBJETIVO:Comprender mejor el impacto del diagnóstico y el tratamiento del cáncer colorrectal en la salud sexual y reproductiva.DISEÑO:Estudio cualitativo de pacientes con cáncer colorrectal de aparición temprana.ENTORNO:Entrevistas individuales semiestructuradas por Zoom a pacientes reclutados mediante muestreo por conveniencia en siete instituciones académicas.PACIENTES:Se entrevistó a 63 personas diagnosticadas con cáncer colorrectal antes de los 50 años entre marzo de 2021 y agosto de 2024.PRINCIPALES MEDIDAS DE RESULTADOS:Perspectivas de los pacientes sobre el impacto del diagnóstico y el tratamiento del cáncer colorrectal en la salud sexual y reproductiva. Los datos se analizaron de forma iterativa mediante un análisis de contenido cualitativo dirigido y convencional.RESULTADOS:Los participantes discutieron los efectos secundarios en la salud sexual y reproductiva derivados de la cirugía, la quimioterapia y la radiación. Estos efectos secundarios variaban en gravedad, ya que algunos no experimentaban casi ninguno y otros se enfrentaban a problemas importantes. Identificaron varios ámbitos, entre ellos los efectos secundarios de la cirugía y el tratamiento, las repercusiones psicológicas, los efectos en las relaciones y las necesidades no satisfechas. Los subámbitos incluían la salud sexual, la salud reproductiva, el malestar emocional, la imagen corporal, los problemas de comunicación, las repercusiones en las relaciones sentimentales, las necesidades de información, el apoyo financiero y las consultas.LIMITACIONES:Los participantes fueron reclutados únicamente en centros médicos académicos, por lo que es posible que las respuestas no reflejen las experiencias de las personas atendidas en entornos no académicos.CONCLUSIONES:La salud sexual y reproductiva son cuestiones fundamentales, pero a menudo se pasan por alto entre los pacientes jóvenes con CCR, con repercusiones significativas en el funcionamiento físico, las relaciones de pareja y el bienestar psicológico. Las directrices actuales para la supervivencia no abordan adecuadamente estas necesidades. Nuestros hallazgos ponen de relieve la importancia del asesoramiento previo al tratamiento y la preservación de la fertilidad, así como la necesidad de un apoyo continuo a la salud mental durante y después del tratamiento del cáncer. (AI-generated translation ).

Indexed as

Colorectal NeoplasmsReproductive HealthSexual Dysfunction, PhysiologicalSexual HealthAdultAge of OnsetBody ImageColorectal Surgical ProceduresFemaleHumansMaleMiddle AgedQualitative ResearchQuality of LifeColorectal cancerEarly-onsetFertilityReproductive healthSexual healthSurvivorship

Identifiers

PMID41676985
PMCPMC13032761

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.