Evidence map›Paper›PMID 41676706›Full record

ArticlebioRxiv : the preprint server for biology2026

Identification and characterization of the functional LolB ortholog in

Krista M Armbruster, Rhea Trickannad, Nichollas E Scott, Nicholas A Pudlo, Jesse W Wotring, Eric C Martens, Jonathan Z Sexton, Nicole M Koropatkin

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Krista M ArmbrusterDepartment of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, MI, 48109, USA.
Rhea TrickannadDepartment of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, MI, 48109, USA.
Nichollas E ScottDepartment of Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, University of Melbourne, Parkville, Victoria, 3000, Australia.ORCID 0000-0003-2556-8316
Nicholas A PudloDepartment of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, MI, 48109, USA.
Jesse W WotringDepartment of Medicinal Chemistry, College of Pharmacy, University of Michigan, Ann Arbor, MI, 48109, USA.
Eric C MartensDepartment of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, MI, 48109, USA.ORCID 0000-0001-6681-2990
Jonathan Z SextonDepartment of Medicinal Chemistry, College of Pharmacy, University of Michigan, Ann Arbor, MI, 48109, USA.ORCID 0000-0002-9244-5888
Nicole M KoropatkinDepartment of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, MI, 48109, USA.ORCID 0000-0002-2459-3336

Funding

Modeling Drug Induced Liver Injury with Patient-Derived Liver Organoids and Microfluidic ChipsR01GM152417 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI ROBERT J FONTANA, Jonathan Zachary Sexton · 2024 to 2026
$1.7M
Laser-based high content imaging microscopeS10OD034245 · OD · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI SEXTON, JONATHAN ZACHARY · 2024 to 2024
$1.4M
Bacteroides use a novel N-acyltransferase for lipoprotein synthesis and survivalR21AI180287 · NIAID · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI KOROPATKIN, NICOLE M · 2024 to 2025
$413k
NIAID NIH HHS R21 AI180287NIGMS NIH HHS R01 GM152417NIH HHS S10 OD034245
6 · The paper itself

Abstract

Bacteroidota are prolific members of the human gut microbiota, influencing overall health through the degradation of various polysaccharides. To aid in this process, these bacteria deploy cell surface lipoproteins, proteins anchored to the membrane by a lipidated N-terminal cysteine. Despite their importance, lipoprotein synthesis and transport in Bacteroidota is not well defined, particularly how lipoproteins reach the outer membrane and cell surface. In

Identifiers

PMID41676706
PMCPMC12889592

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.