Evidence map›Paper›PMID 41676665›Full record

ArticlebioRxiv : the preprint server for biology2026

Duration of Initial Viremia Modulates Functional Properties of HIV-specific T Cell Receptors.

Funsho J Ogunshola, Nishant K Singh, Vincent Butty, Anurag R Mishra, Zacharia Habte, Liza Vecchiarello, Ahmed Fahad, Kate B Juergens, Sophia Cheever, Marius Allombert and 16 more

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

26 authors.

Funsho J OgunsholaRagon Institute of Mass General Brigham, MIT, and Harvard, Cambridge, MA, 02139, USA.ORCID 0000-0002-5655-4905
Nishant K SinghRagon Institute of Mass General Brigham, MIT, and Harvard, Cambridge, MA, 02139, USA.
Vincent ButtyMassachusetts Institute of Technology, Cambridge, MA 02169, USA.
Anurag R MishraRagon Institute of Mass General Brigham, MIT, and Harvard, Cambridge, MA, 02139, USA.
Zacharia HabteRagon Institute of Mass General Brigham, MIT, and Harvard, Cambridge, MA, 02139, USA.
Liza VecchiarelloRagon Institute of Mass General Brigham, MIT, and Harvard, Cambridge, MA, 02139, USA.
Ahmed FahadRagon Institute of Mass General Brigham, MIT, and Harvard, Cambridge, MA, 02139, USA.
Kate B JuergensRagon Institute of Mass General Brigham, MIT, and Harvard, Cambridge, MA, 02139, USA.
Sophia CheeverRagon Institute of Mass General Brigham, MIT, and Harvard, Cambridge, MA, 02139, USA.
Marius AllombertRagon Institute of Mass General Brigham, MIT, and Harvard, Cambridge, MA, 02139, USA.
Anabelle WebberRagon Institute of Mass General Brigham, MIT, and Harvard, Cambridge, MA, 02139, USA.
Alicja Piechocka-TrochaRagon Institute of Mass General Brigham, MIT, and Harvard, Cambridge, MA, 02139, USA.
Nasreen IsmailHIV Pathogenesis Programme, The Doris Duke Medical Research Institute, University of KwaZulu-Natal, 4013 Durban, South Africa.
Anusha NathanRagon Institute of Mass General Brigham, MIT, and Harvard, Cambridge, MA, 02139, USA.
Xiaolong LiRagon Institute of Mass General Brigham, MIT, and Harvard, Cambridge, MA, 02139, USA.
Kavidha ReddyAfrica Health Research Institute, Durban, 4013, South Africa.
Kamini GounderAfrica Health Research Institute, Durban, 4013, South Africa.
Omolara O BaiyegunhiAfrica Health Research Institute, Durban, 4013, South Africa.
David R CollinsRagon Institute of Mass General Brigham, MIT, and Harvard, Cambridge, MA, 02139, USA.
Musie GhebremichaelRagon Institute of Mass General Brigham, MIT, and Harvard, Cambridge, MA, 02139, USA.
Gaurav GaihaRagon Institute of Mass General Brigham, MIT, and Harvard, Cambridge, MA, 02139, USA.
Krista DongRagon Institute of Mass General Brigham, MIT, and Harvard, Cambridge, MA, 02139, USA.
Brandon J DekoskyRagon Institute of Mass General Brigham, MIT, and Harvard, Cambridge, MA, 02139, USA.
Thumbi Ndung'uRagon Institute of Mass General Brigham, MIT, and Harvard, Cambridge, MA, 02139, USA.ORCID 0000-0003-2962-3992
Michael E BirnbaumRagon Institute of Mass General Brigham, MIT, and Harvard, Cambridge, MA, 02139, USA.ORCID 0000-0002-2281-3518
Bruce D WalkerRagon Institute of Mass General Brigham, MIT, and Harvard, Cambridge, MA, 02139, USA.ORCID 0000-0001-6122-9245

Funding

The impact of HIV viral diversity and cellular immunity on HIV pathogenesisP30AI060354 · NIAID · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI ARTHUR Y KIM · 2004 to 2026
$94.4M
VIRUS PRODUCTION COREP30CA014051 · NCI · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI Jacqueline A. Lees · 1985 to 2026
$93.9M
Repertoire-scale T cell antigen identification via peptide-MHC lentivirus displayDP2AI158126 · NIAID · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI BIRNBAUM, MICHAEL · 2020 to 2020
$2.3M
Gates Foundation INV-033558NCI NIH HHS P30 CA014051NIAID NIH HHS DP2 AI158126NIAID NIH HHS P30 AI060354Wellcome Trust
6 · The paper itself

Abstract

Virus-specific CD8

Identifiers

PMID41676665
PMCPMC12889509

What OpenQuestion holds

Textmetadata
LicenceCC0
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.