Evidence map›Paper›PMID 41676594›Full record

ArticlebioRxiv : the preprint server for biology2026

Understanding Iron and Oxidative Stress Response in

Daniel Ajuzie, Seyed A Arshad, Komal S Rasaputra, Bert Debusschere, Elebeoba E May

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Daniel AjuzieDepartment of Biomedical Engineering, University of Houston, Houston, Texas, United States of America.
Seyed A ArshadDepartment of Biomedical Engineering, University of Houston, Houston, Texas, United States of America.
Komal S RasaputraDepartment of Biomedical Engineering, University of Houston, Houston, Texas, United States of America.
Bert DebusschereSandia National Laboratories, Livermore, California, United States of America.
Elebeoba E MayDepartment of Biomedical Engineering, University of Houston, Houston, Texas, United States of America.

Funding

TR&D3: Standards and Tools for Simulator Composition and Credibility portalP41EB023912 · NIBIB · UNIVERSITY OF WASHINGTON · PI HERBERT M. SAURO · 2018 to 2026
$11.4M
NIBIB NIH HHS P41 EB023912
6 · The paper itself

Abstract

Developing effective antimicrobial strategies requires a predictive understanding of bacterial responses to multiple stress conditions which often result in multiple phenotypes. A microbe's survival and proliferation depend on its ability to manage concurrent, dynamically varying stressors within its microenvironment. However, time-resolved predictive models that capture multi-phenotype responses are lacking, and single-phenotype models often fail to accurately replicate a microbe's reaction to mixed stress conditions. In this work, we develop a mechanistic in-silico model of multi-stress response in

Identifiers

PMID41676594
PMCPMC12889586

What OpenQuestion holds

Textmetadata
LicenceCC0
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.