ArticleCurrent pediatrics reports2025
Metabolic Implications of Childhood Cancer.
Article in Current pediatrics reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Impact of exercise interventions on cardiorespiratory fitness in childhood cancer survivors: a systematic review and meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Pooled it
- Microvascular skeletal muscle oxygenation and exercise capacity in childhood cancer survivors compared to healthy controls: a cross-sectional study.Scientific reports · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Purpose of Review: Childhood cancer patients and survivors often suffer from obesity and metabolic syndrome. The purpose of this review is to evaluate the available data on how body composition and metabolism are affected by childhood cancer and its treatment. Recent Findings: Though severity varies among cancers and treatments, childhood cancer patients often exhibit acute changes in metabolism and body composition during the induction of therapy. Particularly prevalent is a decrease in lean mass accompanied by excess adiposity, often called sarcopenic obesity. These metabolic burdens can last for decades after therapy and contribute to future morbidity and mortality. A few promising studies show that dietary and physical activity interventions may reduce these outcomes. Summary: Body composition and metabolic effects occur during cancer treatment and can increase the risk of chronic disease in survivors. More studies are needed to best plan monitoring and intervention strategies to prevent metabolic syndrome and its sequelae in childhood cancer survivors. the course of the disease.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.