Evidence map›Paper›PMID 41676450›Full record

ArticleiMetaOmics2025

MOMMY study profile: An integrative early-life multi-omics cohort in China.

Lin Zhang, Yingzhi Liu, Shilan Wang, Jessica Yuet-Ling Ching, Wing Hung Tam, Ting Fan Leung, Tak Yeung Leung, Paul K S Chan, Joyce W Y Mak, Chun Pan Cheung and 19 more

Abstract read
In one paragraph

Article in iMetaOmics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

29 authors.

Lin ZhangMicrobiota I-Center (MagIC) Hong Kong SAR China.ORCID https://orcid.org/0000-0003-1634-3780
Yingzhi LiuMicrobiota I-Center (MagIC) Hong Kong SAR China.
Shilan WangMicrobiota I-Center (MagIC) Hong Kong SAR China.
Jessica Yuet-Ling ChingMicrobiota I-Center (MagIC) Hong Kong SAR China.
Wing Hung TamDepartment of Obstetrics and Gynaecologist, Faculty of Medicine The Chinese University of Hong Kong Hong Kong SAR China.
Ting Fan LeungDepartment of Paediatrics, Faculty of Medicine The Chinese University of Hong Kong Hong Kong SAR China.
Tak Yeung LeungDepartment of Obstetrics and Gynaecologist, Faculty of Medicine The Chinese University of Hong Kong Hong Kong SAR China.
Paul K S ChanDepartment of Microbiology, Faculty of Medicine The Chinese University of Hong Kong Hong Kong SAR China.
Joyce W Y MakDepartment of Medicine and Therapeutics, Faculty of Medicine The Chinese University of Hong Kong Hong Kong SAR China.
Chun Pan CheungMicrobiota I-Center (MagIC) Hong Kong SAR China.
Hein Min TunMicrobiota I-Center (MagIC) Hong Kong SAR China.
Eugene B ChangDepartment of Medicine, Section of Gastroenterology, Hepatology, and Nutrition University of Chicago Chicago Illinois USA.
Orlando DeLeonDepartment of Medicine, Section of Gastroenterology, Hepatology, and Nutrition University of Chicago Chicago Illinois USA.
Qitao HuangDepartment of Obstetrics and Gynaecologist The First People's Hospital of Foshan, Foshan Guangdong China.
Xiaoqian ChenDepartment of Paediatrics The First People's Hospital of Foshan Foshan China.
Huiyi HuoDepartment of Paediatrics The First People's Hospital of Foshan Foshan China.
Yinglei MiaoDivision of Gastroenterology The First Affiliated Hospital of Kunming Medical University Kunming Yunnan China.
Pui Kuan CheongMicrobiota I-Center (MagIC) Hong Kong SAR China.
Ka Long IpMicrobiota I-Center (MagIC) Hong Kong SAR China.
Yuk Ling YeungDepartment of Obstetrics and Gynaecologist, Faculty of Medicine The Chinese University of Hong Kong Hong Kong SAR China.
Mei Kam ChangDepartment of Paediatrics, Faculty of Medicine The Chinese University of Hong Kong Hong Kong SAR China.
Chunmei LyuShunde Hospital of Southern Medical University, Foshan Guangdong China.
Hongju YangDivision of Gastroenterology The First Affiliated Hospital of Kunming Medical University Kunming Yunnan China.
Bona LiDivision of Gastroenterology The First Affiliated Hospital of Kunming Medical University Kunming Yunnan China.
Yushuo FanDivision of Gastroenterology The First Affiliated Hospital of Kunming Medical University Kunming Yunnan China.
Yang SunDivision of Gastroenterology The First Affiliated Hospital of Kunming Medical University Kunming Yunnan China.
Suhua JiangDepartment of Paediatrics The First People's Hospital of Foshan Foshan China.
Siew Chien NgMicrobiota I-Center (MagIC) Hong Kong SAR China.
Francis Ka Leung ChanMicrobiota I-Center (MagIC) Hong Kong SAR China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Large-scale, prospective birth cohorts capturing the complex interplay between the gut microbiome, host biology, and environmental exposures are crucial to understanding early-life health but remain scarce, particularly within Asian populations. To address this gap, we established the MOMMY cohort (The MOther-infant Microbiota transmission and its link to long terM health of babY), a large, prospective birth cohort uniquely designed to investigate maternal-paternal-infant microbiota transmission and its impact on child health within the understudied Chinese population. MOMMY aims to recruit 20,000 families from three geographically and economically diverse regions across China. This cohort prospectively follows pregnant mothers, fathers, and their infants, with children up to 7 years of age. Since September 2019, we have systematically collected a comprehensive repository of longitudinal biospecimens-including maternal and infant stool, breast milk, cord blood, and parental blood-stored in an accredited biobank. This is complemented by extensive data on environmental exposures, diet, and health outcomes gathered through validated questionnaires and physician assessments. The MOMMY cohort's unique value lies in its unprecedented scale, geographic diversity, and its integrative multi-omics design, which will combine metagenomic, metabolomic, immunologic, and epigenetic data. By creating this unique resource, MOMMY will elucidate how early-life microbial and molecular trajectories, shaped by genetic and environmental factors, influence child development and disease risk, thereby filling a critical gap in global microbiome research.

Indexed as

early lifelongitudinal cohortmicrobiomeMOMMY

Identifiers

PMID41676450
PMCPMC12806111

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.